Rabbit RPS4X Polyclonal Antibody | anti-RPS4X antibody

RPS4X Polyclonal Antibody

Cat. Num. AAA3006178

• Gene Names: RPS4X; S4; CCG2; RPS4; SCAR; SCR10; DXS306
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunocytochemistry
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: RPS4X; Polyclonal Antibody; RPS4X Polyclonal Antibody; 40S ribosomal protein S4; X isoform; SCR10; Single copy abundant mRNA protein; CCG2; RPS4; SCAR; anti-RPS4X antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: RPS4X polyclonal antibody detects endogenous levels of RPS4X protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 263

• Applicable Applications for anti-RPS4X antibody: Western Blot (WB), Immunocytochemistry (ICC)
• Application Notes: WB: 1:500-1:1000; ICC: 1:50-1:200
• Immunogen: Synthetic peptide, corresponding to amino acids 132-177 of Human RPS4X.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of RPS4X polyclonal antibody at 1:500 dilutionLane1:Hela cell lysateLane2:sp2/0 cell lysateLane3:H9C2 cell lysate)

Related Product Information for anti-RPS4X antibody

Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. RPS4Y2 (ribosomal protein S4, Y-linked 2), RPS4Y1 (ribosomal protein S4, Y-linked 1) and RPS4X (ribosomal protein S4, X-linked) are proteins that contain one S4 RNA-binding domain and exist as components of the 40S ribosomal subunit, indicating a possible role in protein synthesis.

NCBI and Uniprot Product Information

• NCBI GI #: 4506725
• NCBI GeneID: 6191
• NCBI Accession #: NP_000998.1
• NCBI GenBank Nucleotide #: NP_000998.1
• UniProt Accession #: P62701
• Molecular Weight: ~ 30kDa
• NCBI Official Full Name: 40S ribosomal protein S4, X isoform
• NCBI Official Synonym Full Names: ribosomal protein S4 X-linked
• NCBI Official Symbol: RPS4X
• NCBI Official Synonym Symbols: S4; CCG2; RPS4; SCAR; SCR10; DXS306
• NCBI Protein Information: 40S ribosomal protein S4, X isoform
• UniProt Protein Name: 40S ribosomal protein S4, X isoform
• Protein Family: 40S ribosomal protein
• UniProt Gene Name: RPS4X
• UniProt Synonym Gene Names: CCG2; RPS4; SCAR
• UniProt Entry Name: RS4X_HUMAN

NCBI Description

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Uniprot Description

RPS4X: Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Protein type: Ribosomal; RNA-binding; Translation

Chromosomal Location of Human Ortholog: Xq13.1

Cellular Component: polysome; small ribosomal subunit; focal adhesion; membrane; ribosome; ribonucleoprotein complex; cytosol

Molecular Function: rRNA binding; structural constituent of ribosome

Biological Process: SRP-dependent cotranslational protein targeting to membrane; translation; positive regulation of translation; viral reproduction; multicellular organismal development; translational termination; viral infectious cycle; cellular protein metabolic process; translational elongation; positive regulation of cell proliferation; translational initiation; mRNA catabolic process, nonsense-mediated decay; gene expression; viral transcription