Rabbit anti-Human RPS11 Polyclonal Antibody | anti-RPS11 antibody

RPS11, ID (RPS11, 40S ribosomal protein S11) (PE)

Cat. Num. AAA6343709

• Gene Names: RPS11; S11
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: RPS11; Polyclonal Antibody; ID (RPS11; 40S ribosomal protein S11) (PE); 40S ribosomal protein S11; anti-RPS11 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-RPS11 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: RPS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87~116 amino acids from the Central region of human RPS11.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of RPS11 Antibody (Center) in A2058 cell line lysates (35ug/lane). RPS11 (arrow) was detected using the purified Pab.)

Related Product Information for anti-RPS11 antibody

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S17) is thought to be involved in the recognition of termination codons. This gene is co-transcribed with a small nucleolar RNA gene, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Product Categories/Family for anti-RPS11 antibody

Antibodies; Ribosomal Proteins

References

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007). Yu, Y., et al. Protein Sci. 14(6):1438-1446(2005). Bouwmeester, T., et al. Nat. Cell Biol. 6(2):97-105(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 4506681
• NCBI GeneID: 6205
• NCBI Accession #: NP_001006.1
• NCBI GenBank Nucleotide #: NM_001015.4
• UniProt Accession #: P62280; P04643; Q498Y6; Q6IRY0; B2R4F5
• Molecular Weight: 18,431 Da
• NCBI Official Full Name: 40S ribosomal protein S11
• NCBI Official Synonym Full Names: ribosomal protein S11
• NCBI Official Symbol: RPS11
• NCBI Official Synonym Symbols: S11
• NCBI Protein Information: 40S ribosomal protein S11
• UniProt Protein Name: 40S ribosomal protein S11
• Protein Family: Ribosomal protein
• UniProt Gene Name: RPS11
• UniProt Entry Name: RS11_HUMAN

NCBI Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]

Uniprot Description

RPS11: a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]

Protein type: Translation; Ribosomal; RNA-binding

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: focal adhesion; membrane; cytoplasm; nucleolus; ribosome; cytosol

Molecular Function: rRNA binding; protein binding; structural constituent of ribosome

Biological Process: osteoblast differentiation; SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translational elongation; viral reproduction; translation; translational initiation; mRNA catabolic process, nonsense-mediated decay; gene expression; viral transcription; translational termination; viral infectious cycle