Rabbit anti-Human, Rat RPL23A Polyclonal Antibody | anti-RPL23A antibody

RPL23A Antibody

Cat. Num. AAA7052369

• Gene Names: RPL23A; L23A; MDA20
• Reactivity: Human, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >95%, Protein G purified
• Synonyms: RPL23A; Polyclonal Antibody; RPL23A Antibody; 60S ribosomal protein L23a (Large ribosomal subunit protein uL23); anti-RPL23A antibody

• Host: Rabbit
• Reactivity: Human, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid

• Applicable Applications for anti-RPL23A antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:200
• Immunogen: Recombinant Human 60S ribosomal protein L23a protein (1-92AA)
• Conjugation: Non-conjugated
• Preservative: 0.03% Proclin 300
• Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Species: Human
• Research Area: Epigenetics and Nuclear Signaling
• Preparation and Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: Rat brain tissueAll lanes: RPL23A antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 18 KDaObserved band size: 18 KDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7052369 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunofluorescent analysis of A549 cells using MBS7052369 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Related Product Information for anti-RPL23A antibody

This protein binds to a specific region on the 26S rRNA.

NCBI and Uniprot Product Information

• NCBI GI #: 17105394
• NCBI GeneID: 6147
• NCBI Accession #: NP_000975.2
• NCBI GenBank Nucleotide #: NM_000984.5
• UniProt Accession #: P62750; P29316; P39024; Q92774; B2R5B2
• NCBI Official Full Name: 60S ribosomal protein L23a
• NCBI Official Synonym Full Names: ribosomal protein L23a
• NCBI Official Symbol: RPL23A
• NCBI Official Synonym Symbols: L23A; MDA20
• NCBI Protein Information: 60S ribosomal protein L23a
• UniProt Protein Name: 60S ribosomal protein L23a
• Protein Family: 60S ribosomal protein
• UniProt Gene Name: RPL23A

NCBI Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L23P family of ribosomal proteins. It is located in the cytoplasm. The protein may be one of the target molecules involved in mediating growth inhibition by interferon. In yeast, the corresponding protein binds to a specific site on the 26S rRNA. This gene is co-transcribed with the U42A, U42B, U101A, and U101B small nucleolar RNA genes, which are located in its third, first, second, and fourth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Uniprot Description

RPL23A: This protein binds to a specific region on the 26S rRNA. Belongs to the ribosomal protein L23P family.

Protein type: Ribosomal; Translation

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: cell-cell adherens junction; cytoplasm; cytosol; nucleolus; nucleus; TORC2 complex

Molecular Function: protein binding; structural constituent of ribosome

Biological Process: cell proliferation; mRNA catabolic process, nonsense-mediated decay; ribosomal large subunit assembly and maintenance; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription