Rabbit anti-Human RPC9 Polyclonal Antibody | anti-RPC9 antibody

RPC9 Antibody

Cat. Num. AAA9609779

• Gene Names: CRCP; RCP; RCP9; RPC9; CGRPRCP; CGRP-RCP
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Synonyms: RPC9; Polyclonal Antibody; RPC9 Antibody; Calcitonin gene related peptide receptor component; Calcitonin gene related peptide receptor component protein; Calcitonin gene-related peptide-receptor component protein; CGRP receptor component protein; CGRP-RCP; CGRP-receptor component protein; CGRPRCP; CRCP; DNA-directed RNA polymerase III subunit RPC9; HsC17; RCP; RCP9; RNA polymerase III subunit C9; RPC9_HUMAN; anti-RPC9 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: RPC9 antibody detects endogenous levels of total RPC9
• Purity/Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Form/Format: Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)
• Sequence Length: 115

• Applicable Applications for anti-RPC9 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:1000-3000
• Immunogen: A synthesized peptide derived from human RPC9
• Subcellular Location: Nucleus. Cell Membrane.
• Tissue Specificity: Ubiquitous. Most prevalent in testis.
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of RPC9 using HuvEc whole cell lysates)

Related Product Information for anti-RPC9 antibody

Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF-Kappa-B through the RIG-I pathway (By similarity).
Subunit Structure: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). Interacts with POLR3H/RPC8. POLR3H/RPC8 and CRCP/RPC9 probably form a Pol III subcomplex.
Similarity: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.

NCBI and Uniprot Product Information

• NCBI GI #: 100913026
• NCBI GeneID: 27297
• NCBI Accession #: NP_001035737.1
• NCBI GenBank Nucleotide #: NM_001040647.1
• UniProt Accession #: O75575; Q3KRA3; Q5HYF1; Q8IXL4; A8MUZ4; A8MW23; B2R4H4; B4E198
• Molecular Weight: Observed: 17 kDa; Predicted: 17 kDa
• NCBI Official Full Name: DNA-directed RNA polymerase III subunit RPC9 isoform b
• NCBI Official Synonym Full Names: CGRP receptor component
• NCBI Official Symbol: CRCP
• NCBI Official Synonym Symbols: RCP; RCP9; RPC9; CGRPRCP; CGRP-RCP
• NCBI Protein Information: DNA-directed RNA polymerase III subunit RPC9
• UniProt Protein Name: DNA-directed RNA polymerase III subunit RPC9
• Protein Family: DNA-directed RNA polymerase
• UniProt Gene Name: CRCP
• UniProt Synonym Gene Names: RNA polymerase III subunit C9; CGRP-RCP; CGRP-receptor component protein; CGRPRCP; HsC17

NCBI Description

This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway ().