Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug A172 cell Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Rabbit anti-Human RORB Polyclonal Antibody | anti-RORB antibody
RORB Antibody
Immunohistochemistry: 1:25-1:100
Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug A172 cell Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Testing Data
(Gel: 6%SDS-PAGE Lysate: 40ug A172 cell Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]
Uniprot Description
RORB: Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter. Belongs to the nuclear hormone receptor family. NR1 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor; DNA-binding
Chromosomal Location of Human Ortholog: 9q22
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding; ligand-dependent nuclear receptor activity; zinc ion binding; sequence-specific DNA binding; steroid hormone receptor activity; transcription factor activity; transcription factor binding
Biological Process: transcription initiation from RNA polymerase II promoter; intracellular receptor-mediated signaling pathway; retinal rod cell development; positive regulation of transcription, DNA-dependent; rhythmic process; regulation of circadian rhythm; eye photoreceptor cell development; visual perception; regulation of transcription, DNA-dependent; retinal cone cell development; retina development in camera-type eye; steroid hormone mediated signaling; gene expression; negative regulation of osteoblast differentiation; negative regulation of transcription, DNA-dependent
Research Articles on RORB
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Product Notes
The RORB rorb (Catalog #AAA9406613) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RORB Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RORB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:200-1:1000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the RORB rorb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RORB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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