Rabbit ROBO4 Polyclonal Antibody | anti-ROBO4 antibody
ROBO4 Antibody
Gene Names
ROBO4; MRB; ECSM4
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
ROBO4; Polyclonal Antibody; ROBO4 Antibody; ECSM4; FLJ20798; Magic roundabout; MGC133352; MGC133353; MRB; Robo 4; ROBO4_HUMAN; Roundabout homolog 4; Roundabout homolog 4 magic roundabout; Roundabout homolog 4 Precursor; Roundabout; axon guidance receptor; homolog 4 (Drosophila); anti-ROBO4 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
ROBO4 Antibody detects endogenous levels of ROBO4.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-ROBO4 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human ROBO4.
Conjugation
Unconjugated
Similarity
Belongs to the immunoglobulin superfamily. ROBO family.
Subunit Structure
Interacts with SLIT2 and ENAH.
Tissue Specificity
Specifically expressed in endothelial cells. Expressed in endothelial and intimal cells of the ascending aorta.
Function
Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-ROBO4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
75,282 Da
NCBI Official Full Name
roundabout homolog 4 isoform 2
NCBI Official Synonym Full Names
roundabout guidance receptor 4
NCBI Official Symbol
ROBO4
NCBI Official Synonym Symbols
MRB; ECSM4
NCBI Protein Information
roundabout homolog 4
UniProt Protein Name
Roundabout homolog 4
Protein Family
UniProt Gene Name
ROBO4
UniProt Entry Name
ROBO4_HUMAN
Uniprot Description
ROBO4: Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. Belongs to the immunoglobulin superfamily. ROBO family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 11q24.2
Cellular Component: external side of plasma membrane; integral to membrane
Molecular Function: receptor activity
Biological Process: angiogenesis; cell differentiation; negative regulation of cell migration; regulation of apoptosis; regulation of cell migration
Research Articles on ROBO4
Similar Products
Product Notes
The ROBO4 robo4 (Catalog #AAA9630227) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ROBO4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ROBO4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the ROBO4 robo4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ROBO4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
