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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver using MBS7603598 (RNH1 antibody) at dilution of 1:50)

Rabbit RNH1 Polyclonal Antibody | anti-RNH1 antibody

RNH1 Rabbit Polyclonal

Gene Names
RNH1; RAI; RNH
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, Functional Assay, Immunoprecipitation
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
RNH1; Polyclonal Antibody; RNH1 Rabbit Polyclonal; anti-RNH1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
447
Applicable Applications for anti-RNH1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), Immunoprecipitation (IP)
Immunogen
Ribonuclease/angiogenin inhibitor 1
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver using MBS7603598 (RNH1 antibody) at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver using MBS7603598 (RNH1 antibody) at dilution of 1:50)

Western Blot (WB)

(L02 cells were subjected to SDS PAGE followed by western blot with MBS7603598 (RNH1 antibody) at dilution of 1:2000)

Western Blot (WB) (L02 cells were subjected to SDS PAGE followed by western blot with MBS7603598 (RNH1 antibody) at dilution of 1:2000)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
49,973 Da
NCBI Official Full Name
RNH1 protein, partial
NCBI Official Synonym Full Names
ribonuclease/angiogenin inhibitor 1
NCBI Official Symbol
RNH1
NCBI Official Synonym Symbols
RAI; RNH
NCBI Protein Information
ribonuclease inhibitor
UniProt Protein Name
Ribonuclease inhibitor
Protein Family
UniProt Gene Name
RNH1
UniProt Synonym Gene Names
PRI; RNH; Placental RNase inhibitor; RAI
UniProt Entry Name
RINI_HUMAN

NCBI Description

Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010]

Uniprot Description

RNH1: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.

Protein type: Inhibitor

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: angiogenin-PRI complex; cytoplasm; nucleoplasm

Molecular Function: protein binding; ribonuclease inhibitor activity

Biological Process: mRNA catabolic process; negative regulation of catalytic activity; regulation of angiogenesis

Research Articles on RNH1

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Product Notes

The RNH1 rnh1 (Catalog #AAA7603598) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RNH1 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RNH1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the RNH1 rnh1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RNH1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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