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Western Blot (WB) (Western blot analysis of RNF130 expression in SKMEL28 (A), HuvEc (B), HeLa (C) whole cell lysates.)

Rabbit RNF130 Polyclonal Antibody | anti-RNF130 antibody

Anti-RNF130 Antibody

Gene Names
RNF130; GP; G1RZFP; GOLIATH
Reactivity
Human, Mouse, Rat, Bovine
Applications
Western Blot, Immunoprecipitation
Purity
The antibody was purified by immunogen affinity chromatography.
Synonyms
RNF130; Polyclonal Antibody; Anti-RNF130 Antibody; E3 ubiquitin-protein ligase RNF130; Goliath homolog; H-Goliath; RING finger protein 130; anti-RNF130 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of RNF130 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
384
Applicable Applications for anti-RNF130 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes
WB (1/500 - 1/1000), IP (1/10 - 1/100)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RNF130. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of RNF130 expression in SKMEL28 (A), HuvEc (B), HeLa (C) whole cell lysates.)

Western Blot (WB) (Western blot analysis of RNF130 expression in SKMEL28 (A), HuvEc (B), HeLa (C) whole cell lysates.)
Related Product Information for anti-RNF130 antibody
Rabbit polyclonal antibody to RNF130

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,456 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase RNF130 isoform 2
NCBI Official Synonym Full Names
ring finger protein 130
NCBI Official Symbol
RNF130
NCBI Official Synonym Symbols
GP; G1RZFP; GOLIATH
NCBI Protein Information
E3 ubiquitin-protein ligase RNF130; goliath homolog; g1-related zinc finger protein
UniProt Protein Name
E3 ubiquitin-protein ligase RNF130
UniProt Gene Name
RNF130
UniProt Synonym Gene Names
H-Goliath
UniProt Entry Name
GOLI_HUMAN

NCBI Description

The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

RNF130: May have a role during the programmed cell death of hematopoietic cells. Acts as an E3 ubiquitin- protein ligase.

Protein type: EC 6.3.2.-; Ubiquitin conjugating system; EC 6.3.2.19; Ubiquitin ligase; Membrane protein, integral; Ligase

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: nucleoplasm; cytoplasm; integral to membrane; nucleus

Molecular Function: zinc ion binding; ubiquitin-protein ligase activity; ligase activity

Biological Process: apoptosis; programmed cell death; protein ubiquitination

Research Articles on RNF130

Similar Products

Product Notes

The RNF130 rnf130 (Catalog #AAA821319) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-RNF130 Antibody reacts with Human, Mouse, Rat, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's RNF130 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). WB (1/500 - 1/1000), IP (1/10 - 1/100). Researchers should empirically determine the suitability of the RNF130 rnf130 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RNF130, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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