Rabbit anti-Mouse RLBP1L2 Polyclonal Antibody | anti-RLBP1L2 antibody

RLBP1L2, CT (CLVS2, C6orf212, C6orf213, RLBP1L2, Clavesin-2, Retinaldehyde-binding protein 1-like 2) (FITC)

Cat. Num. AAA6342228

• Gene Names: CLVS2; RLBP1L2; C6orf212; C6orf213; bA160A10.4
• Reactivity: Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: RLBP1L2; Polyclonal Antibody; CT (CLVS2; C6orf212; C6orf213; Clavesin-2; Retinaldehyde-binding protein 1-like 2) (FITC); CLVS2; Retinaldehyde-binding protein 1-like 2; anti-RLBP1L2 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-RLBP1L2 antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:10-50; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: RLBP1L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the C-terminal region of human RLBP1L2.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(RLBP1L2 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the RLBP1L2 antibody detected the RLBP1L2 protein (arrow).)

Immunohistochemistry (IHC)

(RLBP1L2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RLBP1L2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-RLBP1L2 antibody

Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).

Product Categories/Family for anti-RLBP1L2 antibody

Antibodies; Binding Proteins

References

Katoh, Y., et al. J. Biol. Chem. 284(40):27646-27654(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 71896667
• NCBI GeneID: 134829
• NCBI Accession #: NP_001010852.2
• NCBI GenBank Nucleotide #: NM_001010852.3
• UniProt Accession #: Q5SYC1; Q5SYC0; B3KTG5; B4DHL0; C8UZT4
• Molecular Weight: 38,000 Da
• NCBI Official Full Name: clavesin-2
• NCBI Official Synonym Full Names: clavesin 2
• NCBI Official Symbol: CLVS2
• NCBI Official Synonym Symbols: RLBP1L2; C6orf212; C6orf213; bA160A10.4
• NCBI Protein Information: clavesin-2; retinaldehyde binding protein 1-like 2
• UniProt Protein Name: Clavesin-2
• UniProt Gene Name: CLVS2
• UniProt Synonym Gene Names: C6orf212; C6orf213; RLBP1L2
• UniProt Entry Name: CLVS2_HUMAN

Uniprot Description

RLBP1L2: Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 6q22.31

Cellular Component: clathrin-coated vesicle; early endosome membrane; trans-Golgi network; endosome

Molecular Function: transporter activity

Biological Process: transport; lysosome organization and biogenesis