Western Blot (WB)
(RINL Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RINL antibody detected the RINL protein (arrow).)
Rabbit anti-Human RINL Polyclonal Antibody | anti-RINL antibody
RINL Antibody (N-term)
Reactivity
Human
Applications
Western Blot, ELISA, Flow Cytometry, Functional Assay
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
RINL; Polyclonal Antibody; RINL Antibody (N-term); Ras and Rab interactor-like protein; anti-RINL antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This RINL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human RINL.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.44 (varies by lot)
Sequence Positions
14-43
Sequence Length
566
Applicable Applications for anti-RINL antibody
Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(RINL Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RINL antibody detected the RINL protein (arrow).)
Western Blot (WB)
(RINL Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RINL antibody detected the RINL protein (arrow).)
Flow Cytometry (FC/FACS)
(RINL Antibody (N-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(RINL Antibody (N-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Product Categories/Family for anti-RINL antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
62466
NCBI Official Full Name
ras and Rab interactor-like protein isoform 1
NCBI Official Synonym Full Names
Ras and Rab interactor-like
NCBI Official Symbol
RINL
NCBI Protein Information
ras and Rab interactor-like protein
UniProt Protein Name
Ras and Rab interactor-like protein
Protein Family
UniProt Gene Name
RINL
UniProt Entry Name
RINL_HUMAN
Uniprot Description
RINL: Guanine nucleotide exchange factor (GEF) for RAB5A and RAB22A that activates RAB5A and RAB22A by exchanging bound GDP for free GTP. Plays a role in endocytosis via its role in activating Rab family members. Interacts with RAB5A, RAB22A and MUSK
Protein type: GAPs; GAPs, Rab
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: ruffle; cytoplasmic membrane-bound vesicle; actin cytoskeleton
Molecular Function: guanyl-nucleotide exchange factor activity; GTPase activator activity
Biological Process: protein transport; endocytosis; positive regulation of GTPase activity
Research Articles on RINL
Similar Products
Product Notes
The RINL rinl (Catalog #AAA9201731) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 14-43. The RINL Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RINL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the RINL rinl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RINL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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