Mouse anti-Human RIMKLB Polyclonal Antibody | anti-RIMKLB antibody

RIMKLB (Ribosomal Protein S6 Modification-like Protein B, Beta-citryl-glutamate Synthase B, FAM80B, KIAA1238, N-acetyl-aspartyl-glutamate Synthetase B, NAAG Synthetase B, NAAGS, NAAGS-I)

Cat. Num. AAA649204

• Gene Names: RIMKLB; NAAGS; FAM80B; NAAGS-I
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: RIMKLB; Polyclonal Antibody; RIMKLB (Ribosomal Protein S6 Modification-like Protein B; Beta-citryl-glutamate Synthase B; FAM80B; KIAA1238; N-acetyl-aspartyl-glutamate Synthetase B; NAAG Synthetase B; NAAGS; NAAGS-I); Anti -RIMKLB (Ribosomal Protein S6 Modification-like Protein B; anti-RIMKLB antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human RIMKLB.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MCSSVAAKLWFLTDRRIREDYPQKEILRALKAKCCEEELDFRAVVMDEVVLTIEQGNLGLRINGELITAYPQVVVVRVPTPWVQSDSDITVLRHLEKMGCRLMNRPQAILNCVNKFWTFQELAGHGVPLPDTFSYGGHENFAKMIDEAEVLEFPMVVKNTRGHRGKAVFLARDKHHLADLSHLIRHEAPYLFQKYVKESHGRDVRVIVVGGRVVGTMLRCSTDGRMQSNCSLGGVGMMCSLSEQGKQLAIQVSNILGMDVCGIDLLMKDDGSFCVCEANANPFQEPKKQIQTNKKIPREKTFLLPPS

• Applicable Applications for anti-RIMKLB antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human RIMKLB, aa1-307 (NP_065785.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(FAM80B polyclonal antibody. Western Blot analysis of FAM80B expression in human spleen.)

Western Blot (WB)

(Western Blot analysis of RIMKLB expression in transfected 293T cell line by RIMKLB polyclonal antibody. Lane 1: FAM80B transfected lysate (33.77kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-RIMKLB antibody

Antibodies; Abs to Enzymes; Synthase

NCBI and Uniprot Product Information

• NCBI GI #: 21707208
• NCBI GeneID: 57494
• UniProt Accession #: Q9ULI2; Q8N4P4; Q8WTW6; B7Z834; D3DUV2
• Molecular Weight: 42,464 Da
• NCBI Official Full Name: RIMKLB protein
• NCBI Official Synonym Full Names: ribosomal modification protein rimK-like family member B
• NCBI Official Symbol: RIMKLB
• NCBI Official Synonym Symbols: NAAGS; FAM80B; NAAGS-I
• NCBI Protein Information: beta-citryl-glutamate synthase B; NAAG synthetase B; beta-citrylglutamate synthase B; N-acetylaspartyl-glutamate synthetase B; N-acetyl-aspartyl-glutamate synthetase B; family with sequence similarity 80, member B; ribosomal protein S6 modification-like protein B
• UniProt Protein Name: Beta-citrylglutamate synthase B
• Protein Family: Beta-citrylglutamate synthase
• UniProt Gene Name: RIMKLB
• UniProt Synonym Gene Names: FAM80B; KIAA1238; NAAG synthetase B; NAAGS
• UniProt Entry Name: RIMKB_HUMAN

Uniprot Description

Function: Catalyzes the synthesis of beta-citryl-glutamate and N-acetyl-aspartyl-glutamate. Beta-citryl-glutamate is synthesized more efficiently than N-acetyl-aspartyl-glutamate

By similarity.

Catalytic activity: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate.

Cofactor: Binds 2 magnesium or manganese ions per subunit

By similarity.

Subcellular location: Cytoplasm

By similarity.

Miscellaneous: N-acetylaspartyl-glutamate (NAAG) is the most abundant dipeptide present in vertebrate central nervous system (CNS). Beta-citryl-L-glutamate, a structural analog of NAAG, is present in testis and immature brain

By similarity.

Sequence similarities: Belongs to the RimK family.Contains 1 ATP-grasp domain.

Sequence caution: The sequence BAA86552.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.