Rabbit anti-Human RGS12 Polyclonal Antibody | anti-RGS12 antibody

RGS12 Antibody - C-terminal region

Cat. Num. AAA3220398

• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity purified
• Synonyms: RGS12; Polyclonal Antibody; RGS12 Antibody - C-terminal region; anti-RGS12 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Affinity purified
• Form/Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Sequence: Synthetic peptide located within the following region: STLLPPPSTPQEVPGPSRPGSGTHGSRDLPVNRIIDVDLVTGSAPGRDGG
• Sequence Length: 167

• Applicable Applications for anti-RGS12 antibody: Western Blot (WB)
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RGS12
• Preparation and Storage: For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Host: RabbitTarget Name: RGS12Sample Tissue: Human Hela Whole CellAntibody Dilution: 1.0ug/ml)

Related Product Information for anti-RGS12 antibody

This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined.

Product Categories/Family for anti-RGS12 antibody

Polyclonal

NCBI and Uniprot Product Information

• NCBI GI #: 4506509
• NCBI GeneID: 6002
• NCBI Accession #: NP_002917.1
• NCBI GenBank Nucleotide #: NM_002926.3
• UniProt Accession #: O14924
• Molecular Weight: 156 kDa
• NCBI Official Full Name: regulator of G-protein signaling 12 isoform 2
• NCBI Official Synonym Full Names: regulator of G protein signaling 12
• NCBI Official Symbol: RGS12
• NCBI Protein Information: regulator of G-protein signaling 12
• UniProt Protein Name: Regulator of G-protein signaling 12
• Protein Family: Regulator of G-protein signaling
• UniProt Gene Name: RGS12
• UniProt Synonym Gene Names: RGS12
• UniProt Entry Name: RGS12_HUMAN

NCBI Description

This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

RGS12: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, misc.

Chromosomal Location of Human Ortholog: 4p16.3

Cellular Component: nuclear matrix; condensed nuclear chromosome; cytoplasm; nucleolus; plasma membrane; nucleus

Molecular Function: receptor signaling protein activity; GTPase regulator activity; GTPase activator activity

Biological Process: transcription, DNA-dependent; regulation of catalytic activity; regulation of G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity