Western Blot (WB)
(RGS11 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RGS11 antibody detected the RGS11 protein (arrow).)
Rabbit anti-Human RGS11 Polyclonal Antibody | anti-RGS11 antibody
RGS11 Antibody (Center)
Western Blot (WB)
(RGS11 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RGS11 antibody detected the RGS11 protein (arrow).)
Western Blot (WB)
(RGS11 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RGS11 antibody detected the RGS11 protein (arrow).)
(regulator of G protein signaling) family. Members of the RGS
family act as GTPase-activating proteins on the alpha subunits of
heterotrimeric, signal-transducing G proteins. This protein
inhibits signal transduction by increasing the GTPase activity of G
protein alpha subunits, thereby driving them into their inactive
GDP-bound form. Alternative splicing occurs at this locus and two
transcript variants encoding distinct isoforms have been
identified.
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Saleem, Y., et al. Biochem. Biophys. Res. Commun. 386(1):65-70(2009)
Martin, J., et al. Nature 432(7020):988-994(2004)
Sierra, D.A., et al. Genomics 79(2):177-185(2002)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]
Uniprot Description
RGS11: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: protein complex; cytoplasm; plasma membrane; heterotrimeric G-protein complex
Molecular Function: signal transducer activity; G-protein beta-subunit binding; GTPase activator activity
Biological Process: G-protein coupled receptor protein signaling pathway; regulation of G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity
Research Articles on RGS11
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Product Notes
The RGS11 rgs11 (Catalog #AAA9214611) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 205-234. The RGS11 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RGS11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the RGS11 rgs11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RGS11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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