Rabbit anti-Rat, Human Rgn Polyclonal Antibody | anti-Rgn antibody

Rgn Antibody

Cat. Num. AAA1499334

• Gene Names: Rgn; Rc; GNL; Reguc
• Reactivity: Rat, Human
• Applications: ELISA, Western Blot
• Purity: >95%, Protein G Purified
• Synonyms: Rgn; Polyclonal Antibody; Rgn Antibody; Regucalcin; RC; Smp30; Gluconolactonase (EC:3.1.1.17); GNL; Senescence marker protein 30; SMP-30; anti-Rgn antibody

• Host: Rabbit
• Reactivity: Rat, Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G Purified
• Sequence Length: 299

• Applicable Applications for anti-Rgn antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Recommended dilution: WB:1:500-2000
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Conjugate: Non-conjugated
• Immunogen: Recombinant rat Regucalcin protein
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: Rgn antibody at 8ug/mlLane 1: A549 whole cell lysateLane 2: HCT116 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 33 kDaObserved band size: 33 kDa)

Related Product Information for anti-Rgn antibody

Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities.

NCBI and Uniprot Product Information

• NCBI GI #: 13928740
• NCBI GeneID: 25106
• NCBI Accession #: NP_113734.1
• NCBI GenBank Nucleotide #: NM_031546.1
• UniProt Accession #: Q03336; Q63496; Q925W3; Q9QWP2
• Molecular Weight: 33,390 Da
• NCBI Official Full Name: regucalcin
• NCBI Official Synonym Full Names: regucalcin (senescence marker protein-30)
• NCBI Official Symbol: Rgn
• NCBI Official Synonym Symbols: Rc; GNL; Reguc
• NCBI Protein Information: regucalcin
• UniProt Protein Name: Regucalcin
• Protein Family: Regucalcin
• UniProt Gene Name: Rgn
• UniProt Synonym Gene Names: Smp30; RC; GNL; SMP-30
• UniProt Entry Name: RGN_RAT

NCBI Description

binds calcium ions; induces increased activity of the sarcoplasmic reticulum calcium-transporting ATPase [RGD, Feb 2006]

Uniprot Description

RGN: Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities. Belongs to the SMP-30/CGR1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.1.17

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus

Molecular Function: calcium ion binding; enzyme regulator activity; gluconolactonase activity; zinc ion binding

Biological Process: aging; cellular calcium ion homeostasis; kidney development; L-ascorbic acid biosynthetic process; liver development; negative regulation of apoptosis; negative regulation of cyclic-nucleotide phosphodiesterase activity; negative regulation of epithelial cell proliferation; negative regulation of nitric oxide biosynthetic process; negative regulation of phosphoprotein phosphatase activity; negative regulation of protein amino acid phosphorylation; negative regulation of protein kinase activity; positive regulation of ATPase activity; positive regulation of fatty acid biosynthetic process; positive regulation of GTPase activity; regulation of calcium-mediated signaling; spermatogenesis