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Western Blot (WB) (Western blot analysis of extracts of various cell lines using REXO2 Polyclonal Antibody at dilution of 1:1000.)

Rabbit REXO2 Polyclonal Antibody | anti-REXO2 antibody

REXO2 Polyclonal Antibody

Gene Names
REXO2; RFN; SFN; REX2; CGI-114
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunofluorescence
Purity
Affinity purification
Synonyms
REXO2; Polyclonal Antibody; REXO2 Polyclonal Antibody; CGI-114; REX2; RFN; SFN; anti-REXO2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-REXO2 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IF: 1:50-1:100
Immunogen
Recombinant fusion protein of human REXO2 (NP_0563382)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines using REXO2 Polyclonal Antibody at dilution of 1:1000.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines using REXO2 Polyclonal Antibody at dilution of 1:1000.)

Immunofluorescence (IF)

(Immunofluorescence analysis of L929 cells using REXO2 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.)

Immunofluorescence (IF) (Immunofluorescence analysis of L929 cells using REXO2 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.)

Immunofluorescence (IF)

(Immunofluorescence analysis of U-2 OS cells using REXO2 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.)

Immunofluorescence (IF) (Immunofluorescence analysis of U-2 OS cells using REXO2 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.)
Related Product Information for anti-REXO2 antibody
This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process.
Product Categories/Family for anti-REXO2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,754 Da
NCBI Official Full Name
Homo sapiens RNA exonuclease 2 (REXO2), mRNA
NCBI Official Synonym Full Names
RNA exonuclease 2
NCBI Official Symbol
REXO2
NCBI Official Synonym Symbols
RFN; SFN; REX2; CGI-114
NCBI Protein Information
oligoribonuclease, mitochondrial; REX2, RNA exonuclease 2 homolog; small fragment nuclease
UniProt Protein Name
Oligoribonuclease, mitochondrial
UniProt Gene Name
REXO2
UniProt Synonym Gene Names
SFN; SMFN
UniProt Entry Name
ORN_HUMAN

NCBI Description

This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]

Uniprot Description

REXO2: a 3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role for cellular nucleotide recycling. Two splice variant isoforms have been described: mitochondrial (isoform 1) and nuclear (isoform 2).

Protein type: EC 3.1.-.-; Hydrolase

Chromosomal Location of Human Ortholog: 11q23.2

Cellular Component: focal adhesion; mitochondrion; mitochondrial matrix; nucleolus; mitochondrial intermembrane space; nucleus

Molecular Function: 3'-5'-exoribonuclease activity; nucleic acid binding; 3'-5' exonuclease activity

Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; nucleotide metabolic process

Research Articles on REXO2

Similar Products

Product Notes

The REXO2 rexo2 (Catalog #AAA2565420) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The REXO2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's REXO2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). WB: 1:500-1:2000 IF: 1:50-1:100. Researchers should empirically determine the suitability of the REXO2 rexo2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "REXO2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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