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SDS-Page (Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human heart tissue lysate, Primary antibody:47379(RETREG1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)

Rabbit RETREG1 Polyclonal Antibody | anti-RETREG1 antibody

RETREG1 Antibody

Gene Names
RETREG1; JK1; JK-1; FAM134B
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
RETREG1; Polyclonal Antibody; RETREG1 Antibody; JK1; JK-1; FAM134B; anti-RETREG1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total RETREG1 protein.
Purity/Purification
Antigen affinity purification
Form/Format
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.8 mg/mL (varies by lot)
Sequence Length
497
Applicable Applications for anti-RETREG1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-2000
IHC: 1:50-300
Immunogen
Fusion protein of human RETREG1
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.

SDS-Page

(Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human heart tissue lysate, Primary antibody:47379(RETREG1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)

SDS-Page (Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human heart tissue lysate, Primary antibody:47379(RETREG1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 47379(RETREG1 Antibody) at dilution 1/50.(Original magnification: 200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 47379(RETREG1 Antibody) at dilution 1/50.(Original magnification: 200))

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 47379(RETREG1 Antibody) at dilution 1/50.(Original magnification: 200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 47379(RETREG1 Antibody) at dilution 1/50.(Original magnification: 200))
Related Product Information for anti-RETREG1 antibody
The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Product Categories/Family for anti-RETREG1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55 kDa
NCBI Official Full Name
reticulophagy regulator 1 isoform 1
NCBI Official Synonym Full Names
reticulophagy regulator 1
NCBI Official Symbol
RETREG1
NCBI Official Synonym Symbols
JK1; JK-1; FAM134B
NCBI Protein Information
reticulophagy regulator 1
UniProt Protein Name
Reticulophagy regulator 1
UniProt Gene Name
RETREG1

NCBI Description

The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Uniprot Description

Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).

Research Articles on RETREG1

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Product Notes

The RETREG1 retreg1 (Catalog #AAA9430361) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RETREG1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RETREG1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-2000 IHC: 1:50-300. Researchers should empirically determine the suitability of the RETREG1 retreg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RETREG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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