Rabbit anti-Human RELM-beta Polyclonal Antibody | anti-RETNLB antibody
RELM-beta (Resistin-Like Molecule-beta)(RELM-beta, FIZZ2, RELM-alpha, FIZZ1)
Gene Names
RETNLB; XCP2; FIZZ1; FIZZ2; HXCP2; RELMb; RELMbeta; RELM-beta
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedImmunoaffinity chromatography on a column with immobilized recombinant human RELM-beta.
Synonyms
RELM-beta; Polyclonal Antibody; RELM-beta (Resistin-Like Molecule-beta)(RELM-beta; FIZZ2; RELM-alpha; FIZZ1); Anti -RELM-beta (Resistin-Like Molecule-beta)(RELM-beta; anti-RETNLB antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
C-terminal His-Tagged fusion protein produced in E. coli, it is a 11kD protein containing 90 amino acid residues of the human RELM beta and 12 additional amino acid residues - His-Tag (underlined). The amino acid sequence of the recombinant human RELM beta is 100% homologous to the amino acid sequence of the human RELM beta without signal sequence.
Purity/Purification
Affinity Purified
Immunoaffinity chromatography on a column with immobilized recombinant human RELM-beta.
Immunoaffinity chromatography on a column with immobilized recombinant human RELM-beta.
Form/Format
Sterile filtered and lyophilized from 1mg/ml in 0.05M phosphate buffer, 0.1M NaCl, pH 7.2.
Applicable Applications for anti-RETNLB antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA, Western blotting.
Titer: Defined by indirect ELISA is >1:100,000 for antibody concentration
1mg/ml, 25ng of antigen are coated per well, and is then defined at a point of
maximal decrease of the titration curve.
Titer: Defined by indirect ELISA is >1:100,000 for antibody concentration
1mg/ml, 25ng of antigen are coated per well, and is then defined at a point of
maximal decrease of the titration curve.
Immunogen
Recombinant human RELM-beta.
Reconstitution
Add 0.1ml of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of
the antibody. In this case clarify the solution by centrifugation.
the antibody. In this case clarify the solution by centrifugation.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-RETNLB antibody
RELM-beta (Resistin-Like Molecule-beta) is a member of a recently identified family of secreted proteins containing a conserved cystein-rich C-terminus. The RELM family consists of resistin (also called FIZZ3), RELM-alpha (FIZZ1), RELM-beta (FIZZ2) and RELM-gamma. Only resisistin and RELM-beta were found in humans whereas all four RELM family members were identified in rodents. RELM-beta appears to be produced as a homodimer exclusively by intestinal goblet cells and can be found in high quantities in stool. Remarkably, stool of germ-free mice displaying sterile intestinal tract does not contain RELM-beta until bacterial colonization takes place after pathogen-free mice entered natural environment. Some, but not all, colon carcinoma cell lines secrete RELM-beta into the cell culture supernatant. The physiological function of RELM-beta is not known. High doses of recombinant RELM-beta showed hyperglycemic effects including lowered glucose disposal and increased hepatic glucose production in mice.
Product Categories/Family for anti-RETNLB antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
11,747 Da
NCBI Official Full Name
resistin-like beta
NCBI Official Synonym Full Names
resistin like beta
NCBI Official Symbol
RETNLB
NCBI Official Synonym Symbols
XCP2; FIZZ1; FIZZ2; HXCP2; RELMb; RELMbeta; RELM-beta
NCBI Protein Information
resistin-like beta; OTTHUMP00000215152; found in inflammatory zone 1; colon carcinoma-related gene protein; cysteine-rich secreted protein FIZZ2; cysteine-rich secreted A12-alpha-like protein 1; cysteine-rich secreted protein A12-alpha-like 1; colon and small intestine-specific cysteine-rich protein; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 2
UniProt Protein Name
RELM-beta protein
Protein Family
UniProt Gene Name
RELM-beta
UniProt Entry Name
Q2UXL7_HUMAN
Uniprot Description
resistin-like beta: Probable hormone. Belongs to the resistin/FIZZ family.
Chromosomal Location of Human Ortholog: 3q13.1
Cellular Component: extracellular region
Molecular Function: hormone activity
Biological Process: cell proliferation
Research Articles on RETNLB
Similar Products
Product Notes
The RETNLB relm-beta (Catalog #AAA612785) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RELM-beta (Resistin-Like Molecule-beta)(RELM-beta, FIZZ2, RELM-alpha, FIZZ1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RELM-beta can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA, Western blotting. Titer: Defined by indirect ELISA is >1:100,000 for antibody concentration 1mg/ml, 25ng of antigen are coated per well, and is then defined at a point of maximal decrease of the titration curve. Researchers should empirically determine the suitability of the RETNLB relm-beta for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RELM-beta, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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