Western Blot (WB)
(Western Blot: Sample. Lane1: Mouse Brain Tissue; Lane2: Mouse Kidney Tissue.)
Rabbit anti-Human Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) Polyclonal Antibody | anti-RXFP1 antibody
Polyclonal Antibody to Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1)
MGHHHHHHSGSEF- P LQKLDELDLG SNKIENLPPL IFKDLKELSQ LNLSYNPIQK IQANQFDYLV KLKSLSLEGI EISNIQQRMF RPLMNLSHIY FKKFQYCGYA PHVRSCKPNT DGISSLENLL ASIIQRVFVW VVSAVTCFGN IFVICMRPYI RSENKLYAM
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample. Lane1: Mouse Brain Tissue; Lane2: Mouse Kidney Tissue.)
Western Blot (WB)
(Western Blot: Sample. Lane1: Mouse Brain Tissue; Lane2: Mouse Kidney Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant RXFP1, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant RXFP1, Human.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Stomach Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Stomach Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Liver Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Liver Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Thyroid Cancer Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Thyroid Cancer Tissue)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Uniprot Description
RXFP1: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. Belongs to the G-protein coupled receptor 1 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 4q32.1
Cellular Component: integral component of membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; metal ion binding; protein binding
Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger
Research Articles on RXFP1
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Product Notes
The RXFP1 rxfp1 (Catalog #AAA2002518) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the RXFP1 rxfp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF- P LQKLDELDLG SNKIENLPPL IFKDLKELSQ LNLSYNPIQK IQANQFDYLV KLKSLSLEGI EISNIQQRMF RPLMNLSHIY FKKFQYCGYA PHVRSCKPNT DGISSLENLL ASIIQRVFVW VVSAVTCFGN IFVICMRPYI RSENKLYAM. It is sometimes possible for the material contained within the vial of "Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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