Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using REG1A antibody.)
Rabbit REG1A Polyclonal Antibody | anti-REG1A antibody
REG1A Polyclonal Antibody
Gene Names
REG1A; P19; PSP; PTP; REG; ICRF; PSPS; PSPS1
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
REG1A; Polyclonal Antibody; REG1A Polyclonal Antibody; ICRF; Islet cells regeneration factor; Islet of Langerhans regenerating protein; Lithostathine 1 beta; Lithostathine-1-alpha; P19; Pancreatic stone protein 2; Pancreatic stone protein; Pancreatic thread protein; PSP; PSPS; PSPS1; PSPS2; PTP; REG 1 beta; REG; REG-1-alpha; REG1A_HUMAN; REG1B; Regenerating islet derived protein 1 beta; Regenerating islet-derived protein 1-alpha; Regenerating protein I alpha; REGL; anti-REG1A antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
REG1A polyclonal antibody detects endogenous levels of REG1A protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
166
Applicable Applications for anti-REG1A antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant full length Human REG1A.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using REG1A antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using REG1A antibody.)
Related Product Information for anti-REG1A antibody
The regeneration (Reg) family consists of secretory proteins involved in liver, pancreatic, gastric and intestinal cell proliferation or differentiation. Members of the REG family are divided into four subclasses, designated types I, II, III and IV. They have been implicated in the regulation of cell growth, tumorigenesis and the progression of cancer. Reg Ialpha (regenerating islet-derived I alpha), also known as Lithostathine-1alpha, PSPS, REG, P19 or PTP, is a 166 amino acid protein that contains one C-type lectin domain and belongs to the Reg family of secretory proteins. Expressed at high levels in pancreas and fetal brain and at lower levels in adult brain, Reg Ialpha is thought to inhibit spontaneous calcium carbonate precipitation and may also be associated with regeneration of brain and pancreas tissue, as well as with neuronal sprouting. The gene encoding Reg Ialpha is tandemly clustered with other Reg proteins on a region of human chromosome 2, suggesting that several Reg proteins may have arisen from a gene duplication event.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
~ 25kDa
NCBI Official Full Name
Lithostathine-1-alpha
NCBI Official Synonym Full Names
regenerating family member 1 alpha
NCBI Official Symbol
REG1A
NCBI Official Synonym Symbols
P19; PSP; PTP; REG; ICRF; PSPS; PSPS1
NCBI Protein Information
lithostathine-1-alpha
UniProt Protein Name
Lithostathine-1-alpha
Protein Family
UniProt Gene Name
REG1A
UniProt Synonym Gene Names
PSPS; PSPS1; REG; ICRF; REG; PSP; PTP; REG-1-alpha
UniProt Entry Name
REG1A_HUMAN
NCBI Description
This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008]
Uniprot Description
REG1A: Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 2p12
Molecular Function: growth factor activity; carbohydrate binding
Biological Process: positive regulation of cell proliferation
Research Articles on REG1A
Similar Products
Product Notes
The REG1A reg1a (Catalog #AAA3011272) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The REG1A Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's REG1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the REG1A reg1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "REG1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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