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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7126238(REC8 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200))

Rabbit anti-Human, Mouse REC8 Polyclonal Antibody | anti-REC8 antibody

REC8 Antibody

Gene Names
REC8; Rec8p; REC8L1; HR21spB
Reactivity
Human, Mouse
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
REC8; Polyclonal Antibody; REC8 Antibody; REC8 meiotic recombination protein; anti-REC8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-REC8 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:2000-1:5000
IHC: 1:20-1:100
Immunogen
Fusion protein of human REC8
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7126238(REC8 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7126238(REC8 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using MBS7126238(REC8 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using MBS7126238(REC8 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200))
Product Categories/Family for anti-REC8 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
62,614 Da
NCBI Official Full Name
meiotic recombination protein REC8 homolog
NCBI Official Synonym Full Names
REC8 homolog (yeast)
NCBI Official Symbol
REC8
NCBI Official Synonym Symbols
Rec8p; REC8L1; HR21spB
NCBI Protein Information
meiotic recombination protein REC8 homolog; REC8-like 1; cohesin Rec8p; cohesion rec8p; human homolog of rad21, S. pombe; meiotic recombination protein REC8-like 1; recombination and sister chromatid cohesion protein homolog; meiotic recombination and sis
UniProt Protein Name
Meiotic recombination protein REC8 homolog
UniProt Gene Name
REC8
UniProt Synonym Gene Names
REC8L1
UniProt Entry Name
REC8_HUMAN

NCBI Description

This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

REC8: Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II. Belongs to the rad21 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 14q11.2-q12

Cellular Component: male germ cell nucleus; lateral element; nucleus

Biological Process: meiosis; fertilization; male meiosis I; linear element formation; meiotic recombination; sister chromatid cohesion; spermatogenesis; oocyte maturation; double-strand break repair via homologous recombination; spermatid development

Research Articles on REC8

Similar Products

Product Notes

The REC8 rec8 (Catalog #AAA7126238) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The REC8 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's REC8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). ELISA: 1:2000-1:5000 IHC: 1:20-1:100. Researchers should empirically determine the suitability of the REC8 rec8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "REC8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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