Western Blot (WB)
(RBPJL Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RBPJL antibody detected the RBPJL protein (arrow).)
Rabbit anti-Human RBPJL Polyclonal Antibody | anti-RBPJL antibody
RBPJL Antibody (N-term)
Western Blot (WB)
(RBPJL Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RBPJL antibody detected the RBPJL protein (arrow).)
Western Blot (WB)
(RBPJL Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RBPJL antibody detected the RBPJL protein (arrow).)
Immunohistochemistry (IHC)
(RBPJL Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RBPJL Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(RBPJL Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RBPJL Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(RBPJL Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(RBPJL Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)
transcription factor that binds to DNA sequences almost identical
to that bound by the Notch receptor signalling pathway
transcription factor RBP-J. However, unlike RBP-J, RBP-L does not
interact with Notch receptors. RBP-L has been shown to activate
transcription in concert with Epstein-Barr virus nuclear antigen-2
(EBNA2). The protein encoded by this gene is similar in sequence to
the mouse RPB-L protein and Drosophila suppressor of hairless
protein.
Deloukas, P., et al. Nature 414(6866):865-871(2001)
Nakagawa, H., et al. Oncogene 19(2):210-216(2000)
Tani, S., et al. J. Hum. Genet. 44(1):73-75(1999)
Minoguchi, S., et al. Mol. Cell. Biol. 17(5):2679-2687(1997)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the suppressor of hairless protein family. A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J. The mouse protein has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Uniprot Description
RBPJL: Putative transcription factor, which cooperates with EBNA2 to activate transcription. Belongs to the Su(H) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 20q13.12
Cellular Component: transcription factor complex; nucleus
Molecular Function: transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; signal transduction
Research Articles on RBPJL
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Product Notes
The RBPJL rbpjl (Catalog #AAA9203240) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 8-36. The RBPJL Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RBPJL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the RBPJL rbpjl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RBPJL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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