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Rabbit RBP3 Polyclonal Antibody | anti-RBP3 antibody

RBP3

Gene Names
RBP3; IRBP; RBPI; RP66; D10S64; D10S65; D10S66
Reactivity
Human
Predicted: Rat, Mouse
Applications
ELISA, Western Blot
Purity
Purified By Antigen Affinity Column
Synonyms
RBP3; Polyclonal Antibody; D10S64; D10S65; D10S66; IRBP; RBPI; RP66; anti-RBP3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
4279
Applicable Applications for anti-RBP3 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20,000-80,000
WB: 1:200-1,000
Immunogen
Recombinant fragment corresponding to 897-1114aa of human RBP3.
Cellular Localization
Extracellular Matrix, Secreted
Related Product Information for anti-RBP3 antibody
Retinol-binding protein 3
References
Chen P, Miyake M, Fan Q. et al. CMPK1 and RBP3 are associated with corneal curvature in Asian populations. Hum Mol Genet. 23(22):6129-36 (2014)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
135KD
NCBI Official Full Name
Homo sapiens retinol binding protein 3, interstitial, mRNA
NCBI Official Synonym Full Names
retinol binding protein 3
NCBI Official Symbol
RBP3
NCBI Official Synonym Symbols
IRBP; RBPI; RP66; D10S64; D10S65; D10S66
NCBI Protein Information
retinol-binding protein 3
Protein Family

NCBI Description

Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively. [provided by RefSeq, Jul 2008]

Research Articles on RBP3

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Product Notes

The RBP3 (Catalog #AAA8561113) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RBP3 reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RBP3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20,000-80,000 WB: 1:200-1,000. Researchers should empirically determine the suitability of the RBP3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RBP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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