Western Blot (WB)
(Western Blot analysis of extracts of various cells, using RBP2 antibody.)
Rabbit RBP2 Polyclonal Antibody | anti-RBP2 antibody
RBP2 Polyclonal Antibody
Gene Names
RBP2; CRBP2; RBPC2; CRBPII; CRABP-II
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
RBP2; Polyclonal Antibody; RBP2 Polyclonal Antibody; Retinol-binding protein 2; Cellular retinol-binding protein II; CRBP-II; CRBP2; anti-RBP2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
RBP2 polyclonal antibody detects endogenous levels of RBP2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
134
Applicable Applications for anti-RBP2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200
IHC: 1:50-1:200
IF: 1:50-1:200
Immunogen
Recombinant full length Human RBP2.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using RBP2 antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using RBP2 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver injury using RBP2 antibody at dilution of 1:100 (x40 lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver injury using RBP2 antibody at dilution of 1:100 (x40 lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human gastric using RBP2 antibody at dilution of 1:100 (x40 lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human gastric using RBP2 antibody at dilution of 1:100 (x40 lens).)
Related Product Information for anti-RBP2 antibody
Rb (retinoblastoma protein) is a potent transcriptional regulator that is directly involved with events such as entry into cell division and formation of heterochromatin. RBP2 (Retinoblastoma-binding protein 2), also known as RBBP2, JARID1A (Jumonji/ARID domain-containing protein 1A) or KDM5A, is a nuclear protein that belongs to the JARID1 histone demethylase family. Expressed ubiquitously, RBP2 functions as a histone demethylase that, in conjunction with other proteins, binds directly to the viral-binding domain of Rb, thereby regulating Rb-mediated cell proliferation events. In addition, RBP2 can bind to the Rb-interacting protein rhombotin-2 (LMO2) and, through this interaction, can indirectly modulate Rb activity. Via its demethylase activity, RBP2 can remove methyl residues from Histone H3, thus playing a crucial role in the histone code. RBP2 contains one ARID domain, three PHD-type zinc fingers, one JMJN domain and one JMJC domain through which it conveys its enzymatic activity. Multiple isoforms of RBP2 exist due to alternative splicing events.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 16kDa
NCBI Official Full Name
retinol-binding protein 2
NCBI Official Synonym Full Names
retinol binding protein 2
NCBI Official Symbol
RBP2
NCBI Official Synonym Symbols
CRBP2; RBPC2; CRBPII; CRABP-II
NCBI Protein Information
retinol-binding protein 2
UniProt Protein Name
Retinol-binding protein 2
Protein Family
UniProt Gene Name
RBP2
UniProt Synonym Gene Names
CRBP2; CRBP-II
UniProt Entry Name
RET2_HUMAN
NCBI Description
This gene encodes an abundant protein present in the small intestinal epithelium. It is thought to participate in the uptake and/or intracellular metabolism of vitamin A. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. This protein may also modulate the supply of retinoic acid to the nuclei of endometrial cells during the menstrual cycle. [provided by RefSeq, Aug 2015]
Uniprot Description
RBP2: Intracellular transport of retinol. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Chromosomal Location of Human Ortholog: 3q23
Cellular Component: cytosol
Molecular Function: retinoid binding; transporter activity; retinol binding; retinal binding
Biological Process: phototransduction, visible light; epidermis development; transport; retinoid metabolic process; vitamin A metabolic process
Research Articles on RBP2
Similar Products
Product Notes
The RBP2 rbp2 (Catalog #AAA3011690) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RBP2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RBP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the RBP2 rbp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RBP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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