Rabbit RBM39 Polyclonal Antibody | anti-RBM39 antibody

RBM39 (RNA-binding Motif Protein 39, HCC1, CAPER, RNPC2, FSAP59, CAPERalpha) (AP)

Cat. Num. AAA6435164

• Gene Names: RBM39; HCC1; CAPER; RNPC2; FSAP59; CAPERalpha
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by affinity chromatography.
• Synonyms: RBM39; Polyclonal Antibody; RBM39 (RNA-binding Motif Protein 39; HCC1; CAPER; RNPC2; FSAP59; CAPERalpha) (AP); anti-RBM39 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes RBM39. Species Crossreactivity: human, mouse, rat
• Purity/Purification: Purified by affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-RBM39 antibody: Immunohistochemistry (IHC), Western Blot (WB)
• Application Notes: IHC: 1:50-1:200; WB: 1:200-1:2000; Applications are based on unconjugated antibody.
• Immunogen: Recombinant protein corresponding to human RBM39.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Testing Data

()

Product Categories/Family for anti-RBM39 antibody

Antibodies; RNA Binding Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 336176064
• NCBI GeneID: 9584
• NCBI Accession #: NP_001229528.1
• NCBI GenBank Nucleotide #: NM_001242599.1
• UniProt Accession #: Q14498; Q14499; A2RRD3; A5D8W2; B0BLV3; E1P5S0; E1P5S1
• Molecular Weight: 57,090 Da
• NCBI Official Full Name: RNA-binding protein 39 isoform c
• NCBI Official Synonym Full Names: RNA binding motif protein 39
• NCBI Official Symbol: RBM39
• NCBI Official Synonym Symbols: HCC1; CAPER; RNPC2; FSAP59; CAPERalpha
• NCBI Protein Information: RNA-binding protein 39
• UniProt Protein Name: RNA-binding protein 39
• Protein Family: RNA-binding protein
• UniProt Gene Name: RBM39
• UniProt Synonym Gene Names: HCC1; RNPC2
• UniProt Entry Name: RBM39_HUMAN

NCBI Description

This gene encodes a member of the U2AF65 family of proteins. The encoded protein is found in the nucleus, where it co-localizes with core spliceosomal proteins. It has been shown to play a role in both steroid hormone receptor-mediated transcription and alternative splicing, and it is also a transcriptional coregulator of the viral oncoprotein v-Rel. Multiple transcript variants have been observed for this gene. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Aug 2011]

Uniprot Description

RNPC2: Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1. May be involved in pre-mRNA splicing process. Belongs to the splicing factor SR family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; RNA-binding; Spliceosome

Chromosomal Location of Human Ortholog: 20q11.22

Cellular Component: microtubule cytoskeleton; nucleoplasm; microtubule organizing center; nuclear speck

Molecular Function: protein binding; nucleotide binding

Biological Process: RNA processing; regulation of transcription, DNA-dependent; transcription, DNA-dependent; RNA splicing; mRNA processing