Rabbit anti-Human RBM28 Polyclonal Antibody | anti-RBM28 antibody

RBM28, NT (RBM28, RNA-binding protein 28, RNA-binding motif protein 28) (APC)

Cat. Num. AAA6340752

• Gene Names: RBM28; ANES
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: RBM28; Polyclonal Antibody; NT (RBM28; RNA-binding protein 28; RNA-binding motif protein 28) (APC); RNA-binding motif protein 28; anti-RBM28 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-RBM28 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: RBM28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-99 amino acids from the N-terminal region of human RBM28.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(RBM28 Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the RBM28 antibody detected the RBM28 protein (arrow).)

Related Product Information for anti-RBM28 antibody

The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes. It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product Categories/Family for anti-RBM28 antibody

Antibodies; Binding Proteins

References

Spiegel, R., et al. Eur. J. Endocrinol. 162(6):1021-1025(2010). Nousbeck, J., et al. Am. J. Hum. Genet. 82(5):1114-1121(2008). Damianov, A., et al. Biol. Chem. 387 (10-11), 1455-1460 (2006): Andersen, J.S., et al. Nature 433(7021):77-83(2005). Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 187960109
• NCBI GeneID: 55131
• NCBI Accession #: NP_060547.2; NP_001159607.1
• NCBI GenBank Nucleotide #: NM_018077.2
• UniProt Accession #: Q9NW13; Q53H65; Q96CV3; A4D100; B4DU52; E9PDD9
• Molecular Weight: 69,923 Da
• NCBI Official Full Name: RNA-binding protein 28 isoform 1
• NCBI Official Synonym Full Names: RNA binding motif protein 28
• NCBI Official Symbol: RBM28
• NCBI Official Synonym Symbols: ANES
• NCBI Protein Information: RNA-binding protein 28
• UniProt Protein Name: RNA-binding protein 28
• Protein Family: RNA-binding protein
• UniProt Gene Name: RBM28
• UniProt Entry Name: RBM28_HUMAN

NCBI Description

The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]