Western Blot (WB)
(Rax Antibody (C-term) western blot analysis in Y79 cell line,mouse brain,cerebellum and rat brain,cerebellum tissue lysates (35ug/lane).This demonstrates the Rax antibody detected the Rax protein (arrow).)
Rabbit Rax Polyclonal Antibody | anti-RAX antibody
Rax Antibody (C-term)
Western Blot (WB)
(Rax Antibody (C-term) western blot analysis in Y79 cell line,mouse brain,cerebellum and rat brain,cerebellum tissue lysates (35ug/lane).This demonstrates the Rax antibody detected the Rax protein (arrow).)
Western Blot (WB)
(Rax Antibody (C-term) western blot analysis in Y79 cell line,mouse brain,cerebellum and rat brain,cerebellum tissue lysates (35ug/lane).This demonstrates the Rax antibody detected the Rax protein (arrow).)
Mikkola,I., J. Biol. Chem. 276 (6), 4109-4118 (2001)
Mathers,P.H., Cell. Mol. Life Sci. 57 (2), 186-194 (2000)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a homeobox-containing transcription factor that functions in eye development. The gene is expressed early in the eye primordia, and is required for retinal cell fate determination and also regulates stem cell proliferation. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia, and coloboma.[provided by RefSeq, Oct 2009]
Uniprot Description
RAX: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter. Defects in RAX are the cause of microphthalmia isolated type 3 (MCOP3). Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataractand other abnormalities like cataract may also be present. Belongs to the paired homeobox family. Bicoid subfamily.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 18q21.32
Cellular Component: nucleus
Biological Process: limb development; hypothalamus development; camera-type eye development; visual perception; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; pattern specification process
Disease: Microphthalmia, Isolated 3
Research Articles on RAX
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Product Notes
The RAX rax (Catalog #AAA9211382) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 315-346. The Rax Antibody (C-term) reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's Rax can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the RAX rax for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Rax, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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