Rabbit anti-Human RASSF6 Polyclonal Antibody | anti-RASSF6 antibody

RASSF6 Antibody

Cat. Num. AAA7044209

• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen Affinity Purified
• Synonyms: RASSF6; Polyclonal Antibody; RASSF6 Antibody; Ras association domain-containing protein 6; anti-RASSF6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 303

• Applicable Applications for anti-RASSF6 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: Recommended dilution: IHC: 1:20-1:200
• Species: Human
• Immunogen: Recombinant human Ras association domain-containing protein 6 protein (1-303AA)
• Conjugate: Non-conjugated
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-104643
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7044209 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human prostata cancer cancer using MBS7044209 at dilution 1:100)

Related Product Information for anti-RASSF6 antibody

Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B (By similarity).

NCBI and Uniprot Product Information

• NCBI GI #: 393715061
• NCBI GeneID: 166824
• NCBI Accession #: NP_001257320.1
• NCBI GenBank Nucleotide #: NM_001270391.1
• UniProt Accession #: Q6ZTQ3; Q68DT2; Q6PDA6; Q86WG9; Q86WH0
• Molecular Weight: 35,809 Da
• NCBI Official Full Name: ras association domain-containing protein 6 isoform c
• NCBI Official Synonym Full Names: Ras association domain family member 6
• NCBI Official Symbol: RASSF6
• NCBI Protein Information: ras association domain-containing protein 6
• UniProt Protein Name: Ras association domain-containing protein 6
• Protein Family: Ras association domain-containing protein
• UniProt Gene Name: RASSF6
• UniProt Entry Name: RASF6_HUMAN

NCBI Description

This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]

Uniprot Description

RASSF6: Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 4q13.3

Molecular Function: protein binding