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Testing Data (Sample(30 ug whole cell lysate)A: Raji7.5% SDS PAGEPrimary antibody diluted at 1: 1000)

Rabbit anti-Human, Mouse RAR-gamma Polyclonal Antibody | anti-RAR-gamma antibody

RAR-gamma antibody

Gene Names
RARG; RARC; NR1B3
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Purified by antigen-affinity chromatography.
Synonyms
RAR-gamma; Polyclonal Antibody; RAR-gamma antibody; anti-RAR-gamma antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Sequence Length
454
Applicable Applications for anti-RAR-gamma antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:100-1:250
Immunofluorescence: 1:100-1:200
Immunogen Type
Recombinant protein
Immunogen Description
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 119 and 439 of RAR-gamma
Target Name
RAR-gamma
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

Testing Data

(Sample(30 ug whole cell lysate)A: Raji7.5% SDS PAGEPrimary antibody diluted at 1: 1000)

Testing Data (Sample(30 ug whole cell lysate)A: Raji7.5% SDS PAGEPrimary antibody diluted at 1: 1000)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded gastric cancer, using Retinoic Acid Receptor gamma antibody at 1: 100 dilution.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded gastric cancer, using Retinoic Acid Receptor gamma antibody at 1: 100 dilution.)

Immunofluorescence (IF)

(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using RAR-gamma antibody at 1: 200 dilution.)

Immunofluorescence (IF) (Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using RAR-gamma antibody at 1: 200 dilution.)
Related Product Information for anti-RAR-gamma antibody
Retinoic acid receptors (RARs), such as RARG, are nuclear hormone receptors that act as ligand-dependent transcriptional regulators. In their liganded state, RARs activate transcription, whereas in their nonliganded form, they repress transcription of their target genes. RARs have numerous target genes, which have retinoic response elements in their promoter regions (summary by Walkley et al., 2007 [PubMed 17574023]).[supplied by OMIM]
Product Categories/Family for anti-RAR-gamma antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,931 Da
NCBI Official Full Name
retinoic acid receptor gamma isoform 1
NCBI Official Synonym Full Names
retinoic acid receptor, gamma
NCBI Official Symbol
RARG
NCBI Official Synonym Symbols
RARC; NR1B3
NCBI Protein Information
retinoic acid receptor gamma
UniProt Protein Name
Retinoic acid receptor gamma
UniProt Gene Name
RARG
UniProt Synonym Gene Names
NR1B3; RAR-gamma
UniProt Entry Name
RARG_HUMAN

NCBI Description

This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Uniprot Description

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function ().

Research Articles on RAR-gamma

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Product Notes

The RAR-gamma rarg (Catalog #AAA9404380) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAR-gamma antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RAR-gamma can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Western blotting: 1:500-1:3000 Immunohistochemistry: 1:100-1:250 Immunofluorescence: 1:100-1:200. Researchers should empirically determine the suitability of the RAR-gamma rarg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAR-gamma, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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