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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using RAD54L2 Polyclonal Antibody at dilution 1:40)

Rabbit RAD54L2 Polyclonal Antibody | anti-RAD54L2 antibody

RAD54L2 Polyclonal Antibody

Gene Names
RAD54L2; ARIP4; HSPC325; SRISNF2L
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
RAD54L2; Polyclonal Antibody; RAD54L2 Polyclonal Antibody; ARIP4; HSPC325; SRISNF2L; anti-RAD54L2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.6mg/mL (varies by lot)
Sequence Length
1159
Applicable Applications for anti-RAD54L2 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Recombinant protein of human RAD54L2
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using RAD54L2 Polyclonal Antibody at dilution 1:40)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using RAD54L2 Polyclonal Antibody at dilution 1:40)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human tonsil tissue using RAD54L2 Polyclonal Antibody at dilution 1:40)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human tonsil tissue using RAD54L2 Polyclonal Antibody at dilution 1:40)
Related Product Information for anti-RAD54L2 antibody
Adrenergic receptors (ARs) include four general types (a1, a2, b1 and b2) that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. ARs play a critical role in the development of prostate cancer, and transcriptional activity of AR is partly regulated by coregulatory proteins. RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325 or SRISNF2L, is a 1, 467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is post-translationally sumoylated or phosphorylated upon DNA damage.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
162,769 Da
NCBI Official Full Name
RAD54L2 protein, partial
NCBI Official Synonym Full Names
RAD54-like 2 (S. cerevisiae)
NCBI Official Symbol
RAD54L2
NCBI Official Synonym Symbols
ARIP4; HSPC325; SRISNF2L
NCBI Protein Information
helicase ARIP4; RAD54-like protein 2; androgen receptor-interacting protein 4
UniProt Protein Name
Helicase ARIP4
Protein Family
UniProt Gene Name
RAD54L2
UniProt Synonym Gene Names
ARIP4; KIAA0809
UniProt Entry Name
ARIP4_HUMAN

Uniprot Description

RAD54L2: DNA helicase that modulates androgen receptor (AR)- dependent transactivation in a promoter-dependent manner. Not able to remodel mononucleosomes in vitro. Belongs to the SNF2/RAD54 helicase family.

Protein type: EC 3.6.4.12; Nuclear receptor co-regulator; Helicase; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 3p21.2

Cellular Component: nucleus

Molecular Function: DNA binding; transcription cofactor activity; helicase activity; protein kinase binding; ATP binding

Biological Process: metabolic process

Research Articles on RAD54L2

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Product Notes

The RAD54L2 rad54l2 (Catalog #AAA2526799) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAD54L2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RAD54L2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the RAD54L2 rad54l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAD54L2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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