Immunohistochemistry (IHC)
(Immunochemical staining of human RABGGTA in human stomach with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human RABGGTA Polyclonal Antibody | anti-RABGGTA antibody
Anti-RABGGTA Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
RABGGTA; Polyclonal Antibody; Anti-RABGGTA Antibody; Rabbit Polyclonal; RABGGTA Antibody; Rabbit PAb; Antigen Affinity Purified; Rab geranylgeranyl transferase; a subunit; Anti-PTAR3 Antibody; anti-RABGGTA antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human RABGGTA
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-RABGGTA antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human RABGGTA fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human RABGGTA fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human RABGGTA in human stomach with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human RABGGTA in human stomach with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human RABGGTA in human rectum with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human RABGGTA in human rectum with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-RABGGTA antibody
RABGGTA (Rab Geranylgeranyltransferase Subunit Alpha) is a Protein Coding gene. The RABGGTA gene, located on 14q11.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, fruit fly, mosquito, C.elegans, and frog. RABGGTA catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC, and -CCXX, such as RAB1A, RAB3A, RAB5A, and RAB7A. RABGGTA is widely expressed in the esophagus, lung, and other tissues. Diseases associated with RABGGTA include Choroideremia and Pharynx Squamous Cell Carcinoma. Among its related pathways are TP53 Regulates Transcription of Cell Death Genes and Metabolism of proteins. 182 organisms have orthologs with the human gene RABGGTA.
References
van Bokhoven H, et al. (1996) Cdna cloning and chromosomal localization of the genes encoding the alpha-and beta-subunits of human rab geranylgeranyl transferase: The 3' end of the alpha-subunit gene overlaps with the transglutaminase 1 gene promoter. Genomics 38 (2): 133-140.Song HJ, et al. (1997) The genes encoding geranylgeranyl transferase alpha-subunit and transglutaminase 1 are very closely linked but not functionally related in terminally differentiating keratinocytes. Biochem Biophys Res Commun 235 (1): 10-14.Seabra MC, et al. (1991) Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit. Cell 65 (3): 429-434.
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Product Notes
The RABGGTA (Catalog #AAA8109015) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-RABGGTA Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RABGGTA can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the RABGGTA for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RABGGTA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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