Immunoprecipitation (IP)
(Immunoprecipitation of RABGAP1 transfected lysate using RABGAP1 rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with RABGAP1 purified mouse polyclonal antibody.)
Rabbit anti-Human RABGAP1 Polyclonal Antibody | anti-RABGAP1 antibody
RABGAP1 (Rab GTPase-activating Protein 1, GAP and Centrosome-associated Protein, Rab6 GTPase-activating Protein GAPCenA)
Gene Names
RABGAP1; GAPCENA; TBC1D11; RP11-123N4.2
Reactivity
Human
Applications
Immunoprecipitation
Purity
SerumSerum
Synonyms
RABGAP1; Polyclonal Antibody; RABGAP1 (Rab GTPase-activating Protein 1; GAP and Centrosome-associated Protein; Rab6 GTPase-activating Protein GAPCenA); Anti -RABGAP1 (Rab GTPase-activating Protein 1; anti-RABGAP1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human RABGAP1.
Purity/Purification
Serum
Serum
Serum
Form/Format
Supplied as a liquid.
Sequence
MDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMSLPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQISLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESESERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILETWGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
Applicable Applications for anti-RABGAP1 antibody
Immunoprecipitation (IP)
Application Notes
Suitable for use in Immunoprecipitation.
Immunogen
Full length human RABGAP1, aa1-997 (NP_036329.2).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunoprecipitation (IP)
(Immunoprecipitation of RABGAP1 transfected lysate using RABGAP1 rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with RABGAP1 purified mouse polyclonal antibody.)
Immunoprecipitation (IP)
(Immunoprecipitation of RABGAP1 transfected lysate using RABGAP1 rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with RABGAP1 purified mouse polyclonal antibody.)
Related Product Information for anti-RABGAP1 antibody
RABGAP1 may act as a GTPase-activating protein of RAB6A and play a role in microtubule nucleation by centrosome. It may participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.
Product Categories/Family for anti-RABGAP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
121,737 Da
NCBI Official Full Name
RABGAP1 protein
NCBI Official Synonym Full Names
RAB GTPase activating protein 1
NCBI Official Symbol
RABGAP1
NCBI Official Synonym Symbols
GAPCENA; TBC1D11; RP11-123N4.2
NCBI Protein Information
rab GTPase-activating protein 1; TBC1 domain family, member 11; GAP and centrosome-associated protein; rab6 GTPase-activating protein GAPCenA; Rab6 GTPase activating protein, GAPCenA; rab6 GTPase activating protein (GAP and centrosome-associated)
UniProt Protein Name
Rab GTPase-activating protein 1
Protein Family
UniProt Gene Name
RABGAP1
UniProt Entry Name
RBGP1_HUMAN
Uniprot Description
RABGAP1: May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase- anaphase transition. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs; GAPs, Rab; Autophagy
Chromosomal Location of Human Ortholog: 9q34.11
Cellular Component: centrosome; microtubule associated complex; cytosol
Molecular Function: tubulin binding; protein binding; DNA binding; Rab GTPase binding; GTPase activator activity
Biological Process: cell cycle; positive regulation of GTPase activity
Research Articles on RABGAP1
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Reactivity: Human
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Product Notes
The RABGAP1 rabgap1 (Catalog #AAA641616) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABGAP1 (Rab GTPase-activating Protein 1, GAP and Centrosome-associated Protein, Rab6 GTPase-activating Protein GAPCenA) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RABGAP1 can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP). Suitable for use in Immunoprecipitation. Researchers should empirically determine the suitability of the RABGAP1 rabgap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MDDQPGEKEL VKRSQLDGEG DGPLSNQLSA SSTINPVPLV GLQKPEMSLP VKPGQGDSEA SSPFTPVADE DSVVFSKLTY LGCASVNAPR SEVEALRMMS ILRSQCQISL DVTLSVPNVS EGIVRLLDPQ TNTEIANYPI YKILFCVRGH DGTPESDCFA FTESHYNAEL FRIHVFRCEI QEAVSRILYS FATAFRRSAK QTPLSATAAP QTPDSDIFTF SVSLEIKEDD GKGYFSAVPK DKDRQCFKLR QGIDKKIVIY VQQTTNKELA IERCFGLLLS PGKDVRNSDM HLLDLESMGK SSDGKSYVIT GSWNPKSPHF QVVNEETPKD KVLFMTTAVD LVITEVQEPV RFLLETKVRV CSPNERLFWP FSKRSTTENF FLKLKQIKQR ERKNNTDTLY EVVCLESESE RERRKTTASP SVRLPQSGSQ SSVIPSPPED DEEEDNDEPL LSGSGDVSKE CAEKILETWG ELLSKWHLNL NVRPKQLSSL VRNGVPEALR GEVWQLLAGC HNNDHLVEKY RILITKESPQ DSAITRDINR TFPAHDYFKD TGGDGQDSLY KICKAYSVYD EEIGYCQGQS FLAAVLLLHM PEEQAFSVLV KIMFDYGLRE LFKQNFEDLH CKFYQLERLM QEYIPDLYNH FLDISLEAHM YASQWFLTLF TAKFPLYMVF HIIDLLLCEG ISVIFNVALG LLKTSKDDLL LTDFEGALKF FRVQLPKRYR SEENAKKLME LACNMKISQK KLKKYEKEYH TMREQQAQQE DPIERFEREN RRLQEANMRL EQENDDLAHE LVTSKIALRK DLDNAEEKAD ALNKELLMTK QKLIDAEEEK RRLEEESAQL KEMCRRELDK AESEIKKNSS IIGDYKQICS QLSERLEKQQ TANKVEIEKI RQKVDDCERC REFFNKEGRV KGISSTKEVL DEDTDEEKET LKNQLREMEL ELAQTKLQLV EAECKIQDLE HHLGLALNEV QAAKKTWFNR TLSSIKTATG VQGKETC. It is sometimes possible for the material contained within the vial of "RABGAP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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