Western Blot (WB)
(Anti-RABEPK rabbit polyclonal antibody at 1:500 dilution Lane A: K562 Whole Cell Lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:41 kDa Observed band size:41 kDa)
Rabbit anti-Human RABEPK Polyclonal Antibody | anti-RABEPK antibody
Anti-RABEPK Antibody, Rabbit Polyclonal
Gene Names
RABEPK; p40; RAB9P40; bA65N13.1
Reactivity
Human
Applications
Western Blot
Purity
Protein A & Antigen Affinity
Synonyms
RABEPK; Polyclonal Antibody; Anti-RABEPK Antibody; Rabbit Polyclonal; RABEPK Antibody; Rabbit PAb; Antigen Affinity Purified; Rab9 effector protein with kelch motifs; Anti-bA65N13.1 Antibody; Anti-p40 Antibody; Anti-RAB9P40 Antibody; anti-RABEPK antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human RABEPK
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-RABEPK antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthetic peptide corresponding to the center region of the human RABEPK
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the human RABEPK, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Western Blot (WB)
(Anti-RABEPK rabbit polyclonal antibody at 1:500 dilution Lane A: K562 Whole Cell Lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:41 kDa Observed band size:41 kDa)
Western Blot (WB)
(Anti-RABEPK rabbit polyclonal antibody at 1:500 dilution Lane A: K562 Whole Cell Lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:41 kDa Observed band size:41 kDa)
Related Product Information for anti-RABEPK antibody
RABEPK (Rab9 Effector Protein With Kelch Motifs) is a Protein Coding gene. The RABEPK gene, located on 9q33.3, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, rice, and frog. An important paralog of this gene is HCFC1. RABEPK is a Rab9 effector required for endosome to trans-Golgi network (TGN) transport. RABEPK interacts preferentially with the active (GTP-bound) form of RAB9 GTPase and participates in mannose 6-phosphate receptor trafficking from endosomes to the trans-Golgi network (TGN). RABEPK is widely expressed in the liver, testis, and other tissues. Among its related pathways are Retrograde transport at the Trans-Golgi-Network and Golgi-to-ER retrograde transport. 234 organisms have orthologs with the human gene RABEPK.
References
Ikonomov OC, et al. (2003) Active pikfyve associates with and promotes the membrane attachment of the late endosome-to-trans-golgi network transport factor rab9 effector p40. J Biol Chem 278 (51): 50863-50871.Brass AL, et al. (2008) Identification of host proteins required for hiv infection through a functional genomic screen. Science 319 (5865): 921-926.Aivazian D, et al. (2006) Tip47 is a key effector for rab9 localization. J Cell Biol 173 (6): 917-926.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
372
NCBI Official Full Name
Rab9 effector protein with kelch motifs
NCBI Official Synonym Full Names
Rab9 effector protein with kelch motifs
NCBI Official Symbol
RABEPK
NCBI Official Synonym Symbols
p40; RAB9P40; bA65N13.1
NCBI Protein Information
rab9 effector protein with kelch motifs; Rab9 effector p40; 40 kDa Rab9 effector protein
UniProt Protein Name
Rab9 effector protein with kelch motifs
Protein Family
UniProt Gene Name
RABEPK
UniProt Synonym Gene Names
RAB9P40
UniProt Entry Name
RABEK_HUMAN
Uniprot Description
RABEPK: Rab9 effector required for endosome to trans-Golgi network (TGN) transport. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 9q33.3
Cellular Component: intracellular membrane-bound organelle; plasma membrane; endosome membrane; endosome
Biological Process: receptor-mediated endocytosis; vesicle docking during exocytosis
Research Articles on RABEPK
Similar Products
Product Notes
The RABEPK rabepk (Catalog #AAA8103707) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-RABEPK Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RABEPK can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the RABEPK rabepk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RABEPK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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