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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lung cancer MBS7003471 at dilution 1:100)

Rabbit anti-Human RAB8B Polyclonal Antibody | anti-RAB8B antibody

RAB8B Antibody

Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%,Protein G purified
Synonyms
RAB8B; Polyclonal Antibody; RAB8B Antibody; Ras-related protein Rab-8B; anti-RAB8B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Sequence Length
207
Applicable Applications for anti-RAB8B antibody
ELISA (EIA), Immunohistochemistry (IHC)
Immunogen
Recombinant human Ras-related protein Rab-8B protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26579 / sc-26581 / sc-26579 / sc-26581
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung cancer MBS7003471 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lung cancer MBS7003471 at dilution 1:100)
Related Product Information for anti-RAB8B antibody
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,584 Da
NCBI Official Full Name
ras-related protein Rab-8B
NCBI Official Synonym Full Names
RAB8B, member RAS oncogene family
NCBI Official Symbol
RAB8B
NCBI Protein Information
ras-related protein Rab-8B
UniProt Protein Name
Ras-related protein Rab-8B
Protein Family
UniProt Gene Name
RAB8B
UniProt Entry Name
RAB8B_HUMAN

NCBI Description

RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).[supplied by OMIM, Nov 2010]

Uniprot Description

RAB8B: May be involved in vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells. Belongs to the small GTPase superfamily. Rab family.

Protein type: Motility/polarity/chemotaxis; G protein, monomeric, Rab; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: 15q22.2

Cellular Component: mitochondrion; perinuclear region of cytoplasm; peroxisomal membrane; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane

Molecular Function: GDP binding; GTP binding; GTPase activity; protein binding; receptor binding; TPR domain binding

Biological Process: antigen processing and presentation; cilium biogenesis; positive regulation of adrenocorticotropic hormone secretion; positive regulation of cell projection organization and biogenesis; protein import into peroxisome membrane; protein secretion; small GTPase mediated signal transduction; vesicle docking during exocytosis

Research Articles on RAB8B

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Product Notes

The RAB8B rab8b (Catalog #AAA7003471) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAB8B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RAB8B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the RAB8B rab8b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAB8B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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