Western Blot (WB)
(RAB40C Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RAB40C antibody detected the RAB40C protein (arrow).)
Rabbit anti-Human, Mouse RAB40C Polyclonal Antibody | anti-RAB40C antibody
RAB40C, ID (RAB40C, RARL, RASL8C, Ras-related protein Rab-40C, Rar-like protein, Ras-like protein family member 8C, SOCS box-containing protein RAR3) (Azide free) (HRP)
Gene Names
RAB40C; RARL; RASL8C
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
RAB40C; Polyclonal Antibody; ID (RAB40C; RARL; RASL8C; Ras-related protein Rab-40C; Rar-like protein; Ras-like protein family member 8C; SOCS box-containing protein RAR3) (Azide free) (HRP); SOCS box-containing protein RAR3; anti-RAB40C antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Applicable Applications for anti-RAB40C antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
RAB40C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-149 amino acids from the Central region of human RAB40C.
Conjugate
HRP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(RAB40C Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RAB40C antibody detected the RAB40C protein (arrow).)
Western Blot (WB)
(RAB40C Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RAB40C antibody detected the RAB40C protein (arrow).)
Western Blot (WB)
(RAB40C Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the RAB40C antibody detected the RAB40C protein (arrow).)
Western Blot (WB)
(RAB40C Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the RAB40C antibody detected the RAB40C protein (arrow).)
Related Product Information for anti-RAB40C antibody
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Product Categories/Family for anti-RAB40C antibody
References
Ng, E.L., et al. Brain Res Rev 58(1):236-246(2008). Lettre, G., et al. Nat. Genet. 40(5):584-591(2008). Martin, J., et al. Nature 432(7020):988-994(2004). Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002). Pereira-Leal, J.B., et al. J. Mol. Biol. 313(4):889-901(2001).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,304 Da
NCBI Official Full Name
ras-related protein Rab-40C isoform a
NCBI Official Synonym Full Names
RAB40C, member RAS oncogene family
NCBI Official Symbol
RAB40C
NCBI Official Synonym Symbols
RARL; RASL8C
NCBI Protein Information
ras-related protein Rab-40C; RAR like; RAS-like GTPase; rar-like protein; RAR (RAS like GTPASE) like; RAS-like, family 8, member C; SOCS box-containing protein RAR3; ras-like protein family member 8C
UniProt Protein Name
Ras-related protein Rab-40C
Protein Family
UniProt Gene Name
RAB40C
UniProt Synonym Gene Names
RARL; RASL8C
UniProt Entry Name
RB40C_HUMAN
Uniprot Description
RAB40C: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the small GTPase superfamily. Rab family.
Protein type: G protein, monomeric, Rab; G protein, monomeric
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: perinuclear region of cytoplasm; plasma membrane; endosome membrane
Molecular Function: GTPase activity; GDP binding; GTP binding
Biological Process: regulation of exocytosis; intracellular protein transport; protein secretion; protein ubiquitination; Rab protein signal transduction; vesicle docking during exocytosis
Similar Products
Product Notes
The RAB40C rab40c (Catalog #AAA6339826) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAB40C, ID (RAB40C, RARL, RASL8C, Ras-related protein Rab-40C, Rar-like protein, Ras-like protein family member 8C, SOCS box-containing protein RAR3) (Azide free) (HRP) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RAB40C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the RAB40C rab40c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAB40C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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