Western Blot (WB)
(Anti-RAB14 Picoband antibody, MBS178363, Western blottingAll lanes: Anti RAB14 (MBS178363) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: RAJI Whole Cell Lysate at 40ugLane 3: SMMC Whole Cell Lysate at 40ugPredicted bind size: 24KDObserved bind size: 24KD )
anti-Human, Rat RAB14 Polyclonal Antibody | anti-RAB14 antibody
Anti-RAB14 Antibody
Western Blot (WB)
(Anti-RAB14 Picoband antibody, MBS178363, Western blottingAll lanes: Anti RAB14 (MBS178363) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: RAJI Whole Cell Lysate at 40ugLane 3: SMMC Whole Cell Lysate at 40ugPredicted bind size: 24KDObserved bind size: 24KD )
Western Blot (WB)
(Anti-RAB14 Picoband antibody, MBS178363, Western blottingAll lanes: Anti RAB14 (MBS178363) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: RAJI Whole Cell Lysate at 40ugLane 3: SMMC Whole Cell Lysate at 40ugPredicted bind size: 24KDObserved bind size: 24KD )
Background: Ras-related protein Rab-14 is a protein that in humans is encoded by the RAB14 gene. It is mapped to 9q33.2 based on an alignment of the RAB14 sequence with the genomic sequence. RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes.
NCBI and Uniprot Product Information
NCBI Description
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM, Mar 2009]
Uniprot Description
RAB14: a protein of the GTPase superfamily, Rab family. May be involved in vesicular trafficking and neurotransmitter release. Localized to the inner face of the cell membrane by a lipid-anchor.
Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab
Chromosomal Location of Human Ortholog: 9q33.2
Cellular Component: apical plasma membrane; cytoplasmic vesicle membrane; cytosol; early endosome; early endosome membrane; Golgi apparatus; Golgi membrane; Golgi stack; intracellular; intracellular membrane-bound organelle; late endosome; lysosomal membrane; lysosome; nuclear envelope-endoplasmic reticulum network; perinuclear region of cytoplasm; phagocytic vesicle; plasma membrane; recycling endosome; rough endoplasmic reticulum; trans-Golgi network; trans-Golgi network transport vesicle
Molecular Function: GDP binding; glycoprotein binding; GTP binding; GTPase activity; myosin V binding; protein binding
Biological Process: apical protein localization; body fluid secretion; defense response to bacterium; embryonic development; endocytic recycling; fibroblast growth factor receptor signaling pathway; Golgi to endosome transport; intracellular protein transport; intracellular transport; metabolic process; nucleocytoplasmic transport; regulation of protein localization; small GTPase mediated signal transduction; vesicle-mediated transport
Research Articles on RAB14
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Product Notes
The RAB14 rab14 (Catalog #AAA178363) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-RAB14 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RAB14 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot Concentration: 0.1-0.5ug/ml. Researchers should empirically determine the suitability of the RAB14 rab14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAB14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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