Rabbit anti-Human, Rat Quiescin Q6 Polyclonal Antibody | anti-QSOX1 antibody
Quiescine Q6 Antibody BIOTIN-Conjugated
ELISA: 1:10,000
Western Blot: 1:500
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
quiescin Q6: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In fibroblasts, it may have tumor- suppressing capabilities being involved in growth regulation. Belongs to the quiescin-sulfhydryl oxidase (QSOX) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Oxidoreductase; EC 1.8.3.2
Chromosomal Location of Human Ortholog: 1q24
Cellular Component: extracellular region; extracellular space; Golgi apparatus; integral to Golgi membrane; intercellular bridge; intracellular membrane-bound organelle
Molecular Function: flavin-linked sulfhydryl oxidase activity; protein disulfide isomerase activity
Biological Process: cell redox homeostasis; negative regulation of macroautophagy; platelet degranulation; protein folding
Research Articles on QSOX1
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Product Notes
The QSOX1 qsox1 (Catalog #AAA544676) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Quiescine Q6 Antibody BIOTIN-Conjugated reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Quiescin Q6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Dot Blot: 1:10,000 ELISA: 1:10,000 Western Blot: 1:500. Researchers should empirically determine the suitability of the QSOX1 qsox1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Quiescin Q6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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