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Immunohistochemistry (IHC) (Anti-QSOX2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit QSOX2 Polyclonal Antibody | anti-QSOX2 antibody

Rabbit Polyclonal to Human QSOX2

Gene Names
QSOX2; SOXN; QSCN6L1
Reactivity
Gorilla, Human
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
QSOX2; Polyclonal Antibody; Rabbit Polyclonal to Human QSOX2; Anti-QSOX2 Antibody (Internal) IHC-plus; Quiescin Q6-like protein 1; SOXN; Sulfhydryl oxidase 2; QSCN6L1; Quiescin Q6-like 1; Human QSOX2; anti-QSOX2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gorilla, Human
Clonality
Polyclonal
Specificity
Human QSOX2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
698
Applicable Applications for anti-QSOX2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (20 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 15 amino acid peptide from internal region of human QSOX2. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Marmoset (87%); Mouse, Rat, Dog, Elephant, Horse (80%).
Immunogen Type
Synthetic peptide
Immunogen
QSOX2 antibody was raised against synthetic 15 amino acid peptide from internal region of human QSOX2. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Marmoset (87%); Mouse, Rat, Dog, Elephant, Horse (80%).
Antigen Modification
Internal
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-QSOX2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-QSOX2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-QSOX2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-QSOX2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
77,529 Da
NCBI Official Full Name
sulfhydryl oxidase 2
NCBI Official Synonym Full Names
quiescin Q6 sulfhydryl oxidase 2
NCBI Official Symbol
QSOX2
NCBI Official Synonym Symbols
SOXN; QSCN6L1
NCBI Protein Information
sulfhydryl oxidase 2; quiescin Q6-like 1; quiescin Q6-like protein 1; neuroblastoma-derived sulfhydryl oxidase
UniProt Protein Name
Sulfhydryl oxidase 2
Protein Family
UniProt Gene Name
QSOX2
UniProt Synonym Gene Names
QSCN6L1; SOXN
UniProt Entry Name
QSOX2_HUMAN

NCBI Description

QSOX2 is a member of the sulfhydryl oxidase/quiescin-6 (Q6) family (QSOX1; MIM 603120) that regulates the sensitization of neuroblastoma cells for IFN-gamma (IFNG; MIM 147570)-induced cell death (Wittke et al., 2003 [PubMed 14633699]).[supplied by OMIM, Jun 2009]

Uniprot Description

QSCN6L1: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. Also seems to play a role in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis. Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.

Protein type: Apoptosis; EC 1.8.3.2; Oxidoreductase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: nuclear membrane; integral to membrane; extracellular region; plasma membrane

Molecular Function: thiol oxidase activity

Biological Process: cell redox homeostasis

Research Articles on QSOX2

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Product Notes

The QSOX2 qsox2 (Catalog #AAA244030) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human QSOX2 reacts with Gorilla, Human and may cross-react with other species as described in the data sheet. AAA Biotech's QSOX2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (20 ug/ml). Researchers should empirically determine the suitability of the QSOX2 qsox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "QSOX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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