Western Blot (WB)
(WB Suggested Anti-Pygm AntibodyTitration: 1.0 ug/mlPositive Control: Mouse Heart)
Rabbit Pygm Polyclonal Antibody | anti-PYGM antibody
Pygm antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-Pygm AntibodyTitration: 1.0 ug/mlPositive Control: Mouse Heart)
Western Blot (WB)
(WB Suggested Anti-Pygm AntibodyTitration: 1.0 ug/mlPositive Control: Mouse Heart)
Target Description: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a glycolysis enzyme found in muscle. Highly similar enzymes encoded by different genes are found in liver and brain. The encoded protein is involved in regulating the breakdown of glycogen to glucose-1-phosphate, which is necessary for ATP generation. [provided by RefSeq, Dec 2015]
Uniprot Description
PYGM: an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. Dimers associate into a tetramer to form the enzymatically active phosphorylase A. Phosphorylation of Ser-14 converts phosphorylase B (unphosphorylated) to phosphorylase A.
Protein type: Phosphorylase; Transferase; Endoplasmic reticulum; Carbohydrate Metabolism - starch and sucrose; EC 2.4.1.1
Cellular Component: sarcoplasmic reticulum; cytoplasm; Z disc
Molecular Function: transferase activity; transferase activity, transferring glycosyl groups; glycogen phosphorylase activity; phosphorylase activity; nucleotide binding; drug binding; carbohydrate binding; catalytic activity; pyridoxal phosphate binding; AMP binding
Biological Process: cellular calcium ion homeostasis; glycogen metabolic process; response to organic substance; response to cAMP; glycogen catabolic process; metabolic process; carbohydrate metabolic process; response to hypoxia
Research Articles on PYGM
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Product Notes
The PYGM pygm (Catalog #AAA3209118) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Pygm antibody - C-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's Pygm can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the PYGM pygm for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: KNPREWTRMV IRNIATSGKF SSDRTIAQYA REIWGVEPSR QRLPAPDEKI. It is sometimes possible for the material contained within the vial of "Pygm, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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