Western Blot (WB)
(Western Blot analysis of PVRL1 expression in transfected 293T cell line by PVRL1 polyclonal antibody. Lane 1: PVRL1 transfected lysate (39.1kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human PVRL1 Polyclonal Antibody | anti-PVRL1 antibody
PVRL1 (CD111, Poliovirus Receptor-related Protein 1, Herpes Virus Entry Mediator C, Herpes virus Entry Mediator C, HveC, Herpes virus Ig-like Receptor, HIgR, Nectin-1, HVEC, PRR1) APC
Gene Names
NECTIN1; ED4; PRR; HIgR; HV1S; HVEC; OFC7; PRR1; PVRR; CD111; PVRL1; PVRR1; SK-12; CLPED1; nectin-1
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PVRL1; Polyclonal Antibody; PVRL1 (CD111; Poliovirus Receptor-related Protein 1; Herpes Virus Entry Mediator C; Herpes virus Entry Mediator C; HveC; Herpes virus Ig-like Receptor; HIgR; Nectin-1; HVEC; PRR1) APC; anti-PVRL1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PVRL1.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Sequence Length
352
Applicable Applications for anti-PVRL1 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human PVRL1, aa1-352 (NP_976031.1).
Immunogen Sequence
MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITAFCQLIYPGKGRTRARMF
Conjugate
APC
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of PVRL1 expression in transfected 293T cell line by PVRL1 polyclonal antibody. Lane 1: PVRL1 transfected lysate (39.1kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of PVRL1 expression in transfected 293T cell line by PVRL1 polyclonal antibody. Lane 1: PVRL1 transfected lysate (39.1kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-PVRL1 antibody
Nectin-1, also known as CD111 antigen, Poliovirus receptor-related protein 1(PRR-1) and Herpes virus entry mediator C (HVEC), is a 110kD type I transmembrane glycoprotein. Two additional splice forms (another type I transmembrane protein and a secreted protein) also exist. All three isoforms share the aa residues from (aa31-334). Nectin-1 is widely expressed in numerous tissues. It is a Ca2+-independent cell adhesion molecule that is a member of the Ig superfamily. The aa sequence of the human Nectin-1 extracellular domain is 93% and 96% identical to that of mouse and porcine Nectin-1, respectively.
Product Categories/Family for anti-PVRL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
nectin-1 isoform 3
NCBI Official Synonym Full Names
nectin cell adhesion molecule 1
NCBI Official Symbol
NECTIN1
NCBI Official Synonym Symbols
ED4; PRR; HIgR; HV1S; HVEC; OFC7; PRR1; PVRR; CD111; PVRL1; PVRR1; SK-12; CLPED1; nectin-1
NCBI Protein Information
nectin-1
UniProt Protein Name
Poliovirus receptor-related protein 1
UniProt Gene Name
PVRL1
UniProt Synonym Gene Names
HVEC; PRR1; Herpesvirus entry mediator C; HveC; HIgR
UniProt Entry Name
PVRL1_HUMAN
NCBI Description
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]
Research Articles on PVRL1
Similar Products
Product Notes
The PVRL1 pvrl1 (Catalog #AAA6391518) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PVRL1 (CD111, Poliovirus Receptor-related Protein 1, Herpes Virus Entry Mediator C, Herpes virus Entry Mediator C, HveC, Herpes virus Ig-like Receptor, HIgR, Nectin-1, HVEC, PRR1) APC reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PVRL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PVRL1 pvrl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PVRL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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