Rabbit anti-Human PURG Polyclonal Antibody | anti-PURG antibody

PURG, CT (PURG, Purine-rich element-binding protein gamma) (APC)

Cat. Num. AAA6339174

• Gene Names: PURG; PURG-A; PURG-B
• Reactivity: Human
• Applications: Flow Cytometry, Functional Assay, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: PURG; Polyclonal Antibody; CT (PURG; Purine-rich element-binding protein gamma) (APC); Purine-rich element-binding protein gamma; anti-PURG antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-PURG antibody: Flow Cytometry (FC/FACS), FLISA, Western Blot (WB)
• Application Notes: FC/FACS: 1:10-50; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: PURG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human PURG.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(PURG Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PURG antibody detected the PURG protein (arrow).)

Flow Cytometry (FC/FACS)

(PURG Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Related Product Information for anti-PURG antibody

The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. PURG lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. Two transcript variants encoding different isoforms have been found for this gene.

Product Categories/Family for anti-PURG antibody

Antibodies; Binding Proteins

References

Liu, H., et al. Nucleic Acids Res. 30(11):2417-2426(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 62865862
• NCBI GeneID: 29942
• NCBI Accession #: NP_001015508.1; NP_037489.1
• NCBI GenBank Nucleotide #: NM_001015508.1
• UniProt Accession #: Q9UJV8; Q8TE64
• Molecular Weight: 39,556 Da
• NCBI Official Full Name: purine-rich element-binding protein gamma isoform B
• NCBI Official Synonym Full Names: purine-rich element binding protein G
• NCBI Official Symbol: PURG
• NCBI Official Synonym Symbols: PURG-A; PURG-B
• NCBI Protein Information: purine-rich element-binding protein gamma; Pur-gamma
• UniProt Protein Name: Purine-rich element-binding protein gamma
• Protein Family: Purine-rich element-binding protein
• UniProt Gene Name: PURG
• UniProt Entry Name: PURG_HUMAN

NCBI Description

The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

PURG: The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 8p11

Cellular Component: nucleus

Molecular Function: DNA binding