Western Blot (WB)
(Recommended PTRF Antibody Titration: 0.625ug/ml)
Rabbit PTRF Polyclonal Antibody | anti-PTRF antibody
PTRF antibody
Western Blot (WB)
(Recommended PTRF Antibody Titration: 0.625ug/ml)
Western Blot (WB)
(Recommended PTRF Antibody Titration: 0.625ug/ml)
Immunohistochemistry (IHC)
(Paraffin embedded mouse vessel and adipocytes (skeletal muscle) tissue, tested with an antibody Dilution of 5 ug/ml.)
Immunohistochemistry (IHC)
(Paraffin embedded mouse vessel and adipocytes (skeletal muscle) tissue, tested with an antibody Dilution of 5 ug/ml.)
Western Blot (WB)
(Lane 1: 50ug mouse embryonic fibroblast lysate Lane 2: 50ug mouse PTRF-KO embryonic fibroblast lysate Lane 3: 50ug mouse PTRF-KO embryonic fibroblast lysate+DYKDDDDK-PTRF protein Primary Antibody Dilution: 1:1000 Secondary Antibody: Donkey anti-Rabbit-HRP Secondary Antibody Dilution: 1:10000)
Western Blot (WB)
(Lane 1: 50ug mouse embryonic fibroblast lysate Lane 2: 50ug mouse PTRF-KO embryonic fibroblast lysate Lane 3: 50ug mouse PTRF-KO embryonic fibroblast lysate+DYKDDDDK-PTRF protein Primary Antibody Dilution: 1:1000 Secondary Antibody: Donkey anti-Rabbit-HRP Secondary Antibody Dilution: 1:10000)
NCBI and Uniprot Product Information
Uniprot Description
PTRF: Plays an important role in caveolae formation and organization. Required for the sequestration of mobile caveolin into immobile caveolae. Termination of transcription by RNA polymerase I involves pausing of transcription by TTF1, and the dissociation of the transcription complex, releasing pre-rRNA and RNA polymerase I from the template. PTRF is required for dissociation of the ternary transcription complex. Defects in PTRF are the cause of congenital generalized lipodystrophy type 4 (CGL4). It is a disorder characterized by the association of congenital generalized lipodystrophy with muscular dystrophy and cardiac anomalies. Congenital generalized lipodystrophy is characterized by a near complete absence of adipose tissue, extreme insulin resistance, hypertriglyceridemia, hepatic steatosis and early onset of diabetes. Belongs to the PTRF/SDPR family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription initiation complex
Cellular Component: protein complex; mitochondrion; intracellular membrane-bound organelle; membrane; endoplasmic reticulum; cytoplasm; plasma membrane; caveola; nucleus
Molecular Function: rRNA binding; rRNA primary transcript binding; RNA binding
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; transcription initiation from RNA polymerase I promoter; termination of RNA polymerase I transcription; transcription termination
Research Articles on PTRF
Similar Products
Product Notes
The PTRF ptrf (Catalog #AAA834686) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PTRF can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.625 ug/ml. Researchers should empirically determine the suitability of the PTRF ptrf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTRF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
