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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human melanoma cancer using MBS7105061 at dilution of 1:100)

Rabbit anti-Human PTGIS Polyclonal Antibody | anti-PTGIS antibody

PTGIS Antibody

Gene Names
PTGIS; CYP8; PGIS; PTGI; CYP8A1
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%, Protein G purified
Synonyms
PTGIS; Polyclonal Antibody; PTGIS Antibody; Prostacyclin synthase; Prostaglandin I2 synthase; CYP8; CYP8A1; anti-PTGIS antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
500
Applicable Applications for anti-PTGIS antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:20-1:200
Immunogen
Recombinant Human Prostacyclin synthase protein (113-199AA)
Conjugation
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human melanoma cancer using MBS7105061 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human melanoma cancer using MBS7105061 at dilution of 1:100)
Related Product Information for anti-PTGIS antibody
Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).
Product Categories/Family for anti-PTGIS antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57,104 Da
NCBI Official Full Name
prostacyclin synthase
NCBI Official Synonym Full Names
prostaglandin I2 synthase
NCBI Official Symbol
PTGIS
NCBI Official Synonym Symbols
CYP8; PGIS; PTGI; CYP8A1
NCBI Protein Information
prostacyclin synthase
UniProt Protein Name
Prostacyclin synthase
Protein Family
UniProt Gene Name
PTGIS
UniProt Synonym Gene Names
CYP8; CYP8A1

NCBI Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008]

Uniprot Description

Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).

Research Articles on PTGIS

Similar Products

Product Notes

The PTGIS ptgis (Catalog #AAA7105061) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTGIS Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTGIS can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:20-1:200. Researchers should empirically determine the suitability of the PTGIS ptgis for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTGIS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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