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Rabbit PTGFRN Polyclonal Antibody | anti-PTGFRN antibody

PTGFRN Antibody

Gene Names
PTGFRN; FPRP; CD315; EWI-F; CD9P-1; SMAP-6
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
PTGFRN; Polyclonal Antibody; PTGFRN Antibody; CD315; CD9 partner 1; CD9P-1; CD9P1; EWI F; EWI-F; FLJ11001; FPRP; FPRP_HUMAN; Glu Trp Ile EWI motif containing protein F; Glu-Trp-Ile EWI motif-containing protein F; KIAA1436; Prostaglandin F2 alpha receptor associated protein; Prostaglandin F2 alpha receptor regulatory protein; Prostaglandin F2 receptor inhibitor; Prostaglandin F2 receptor negative regulator; Prostaglandin F2-alpha receptor regulatory protein; Prostaglandin F2-alpha receptor-associated protein; Ptgfrn; SMAP 6; anti-PTGFRN antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
PTGFRN Antibody detects endogenous levels of PTGFRN.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-PTGFRN antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human PTGFRN.
Conjugation
Unconjugated
Subunit Structure
Interacts with CD9 and CD81. Part of a complex composed of CD9, CD81 and IGSF8 (By similarity). Also seems to interact with CD63, CD82 and CD151.
Function
Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration (By similarity).
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
98,556 Da
NCBI Official Full Name
prostaglandin F2 receptor negative regulator
NCBI Official Synonym Full Names
prostaglandin F2 receptor inhibitor
NCBI Official Symbol
PTGFRN
NCBI Official Synonym Symbols
FPRP; CD315; EWI-F; CD9P-1; SMAP-6
NCBI Protein Information
prostaglandin F2 receptor negative regulator; CD9 partner 1; glu-Trp-Ile EWI motif-containing protein F; prostaglandin F2-alpha receptor regulatory protein; prostaglandin F2-alpha receptor-associated protein
UniProt Protein Name
Prostaglandin F2 receptor negative regulator
UniProt Gene Name
PTGFRN
UniProt Synonym Gene Names
CD9P1; EWIF; FPRP; KIAA1436; CD9P-1; EWI-F
UniProt Entry Name
FPRP_HUMAN

Uniprot Description

PTGFRN: Inhibits the binding of prostaglandin F2-alpha (PGF2- alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur.

Protein type: Membrane protein, integral; Cytoskeletal

Chromosomal Location of Human Ortholog: 1p13.1

Cellular Component: Golgi apparatus; endoplasmic reticulum membrane; cell surface; integral to membrane

Molecular Function: protein binding

Research Articles on PTGFRN

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Product Notes

The PTGFRN ptgfrn (Catalog #AAA9630149) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTGFRN Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PTGFRN can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the PTGFRN ptgfrn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTGFRN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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