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Western Blot (WB) (Western blot analysis PTGDS2 using Jurkat whole cell lysates)

Rabbit anti-Human PTGDS2 Polyclonal Antibody | anti-PTGDS2 antibody

PTGDS2 Antibody

Gene Names
HPGDS; GSTS; PGD2; PGDS; GSTS1; GSTS1-1
Reactivity
Human
Applications
Western Blot
Synonyms
PTGDS2; Polyclonal Antibody; PTGDS2 Antibody; HPGDS; Glutathione S-transferase; GST class-sigma; GSTS1-1; H-PGDS; PGD2; PGDS; GSTS; Prostaglandin-H2 D-isomerase; anti-PTGDS2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
PTGDS2 Antibody detects endogenous levels of total PTGDS2
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
199
Applicable Applications for anti-PTGDS2 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000-3000
Immunogen
A synthesized peptide derived from human PTGDS2
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis PTGDS2 using Jurkat whole cell lysates)

Western Blot (WB) (Western blot analysis PTGDS2 using Jurkat whole cell lysates)
Product Categories/Family for anti-PTGDS2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,344 Da
NCBI Official Full Name
hematopoietic prostaglandin D synthase
NCBI Official Synonym Full Names
hematopoietic prostaglandin D synthase
NCBI Official Symbol
HPGDS
NCBI Official Synonym Symbols
GSTS; PGD2; PGDS; GSTS1; GSTS1-1
NCBI Protein Information
hematopoietic prostaglandin D synthase
UniProt Protein Name
Hematopoietic prostaglandin D synthase
UniProt Gene Name
HPGDS
UniProt Synonym Gene Names
GSTS; PGDS; PTGDS2; H-PGDS
UniProt Entry Name
HPGDS_HUMAN

NCBI Description

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. [provided by RefSeq, Jul 2008]

Uniprot Description

Ptgds2: Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. Belongs to the GST superfamily. Sigma family.

Protein type: EC 2.5.1.18; EC 5.3.99.2; Isomerase; Lipid Metabolism - arachidonic acid

Chromosomal Location of Human Ortholog: 4q22.3

Cellular Component: cytoplasm; cytosol

Molecular Function: calcium ion binding; glutathione transferase activity; magnesium ion binding; prostaglandin-D synthase activity; protein binding; protein homodimerization activity

Biological Process: cyclooxygenase pathway; locomotory behavior; prostaglandin metabolic process

Research Articles on PTGDS2

Similar Products

Product Notes

The PTGDS2 hpgds (Catalog #AAA9419384) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTGDS2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTGDS2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the PTGDS2 hpgds for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTGDS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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