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Rabbit PSMB2 Polyclonal Antibody | anti-PSMB2 antibody

Rabbit polyclonal PSMB2 antibody (biotin)

Gene Names
PSMB2; HC7-I
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Purified by Ammonium Sulfate precipitation
Synonyms
PSMB2; Polyclonal Antibody; Rabbit polyclonal PSMB2 antibody (biotin); PSMB2 antibody (biotin); anti-PSMB2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Ammonium Sulfate precipitation
Form/Format
Supplied with 0.03% Proclin 300, 50% Glycerol and 0.01M PBS, PH 7.4
Sequence Length
201
Applicable Applications for anti-PSMB2 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Immunogen
PSMB2 antibody (Biotin) was raised in Rabbit using recombinant human Proteasome subunit beta type-2 protein as the immunogen
Cross-Reactivity
Human
Conjugate
Biotin
Preparation and Storage
Store at 4 degree C for short term storage and -20 degree C for long term storage. Avoid repeat freeze/thaw cycles.
Product Categories/Family for anti-PSMB2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
22,836 Da
NCBI Official Full Name
PSMB2
NCBI Official Synonym Full Names
proteasome subunit beta 2
NCBI Official Symbol
PSMB2
NCBI Official Synonym Symbols
HC7-I
NCBI Protein Information
proteasome subunit beta type-2
UniProt Protein Name
Proteasome subunit beta type-2
Protein Family
UniProt Gene Name
PSMB2

NCBI Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

Uniprot Description

PSMB2: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit has a trypsin-like activity. Belongs to the peptidase T1B family.

Protein type: Cell cycle regulation; EC 3.4.25.1; Protease; Proteasome complex

Chromosomal Location of Human Ortholog: 1p34.3

Cellular Component: cytosol; membrane; nucleoplasm; nucleus; proteasome complex; proteasome core complex

Molecular Function: protein binding

Biological Process: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; MAPKKK cascade; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of amino acid metabolic process; regulation of mRNA stability; stimulatory C-type lectin receptor signaling pathway; T cell receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; Wnt receptor signaling pathway, planar cell polarity pathway

Research Articles on PSMB2

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Product Notes

The PSMB2 psmb2 (Catalog #AAA5307167) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PSMB2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the PSMB2 psmb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSMB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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