Rabbit Pseudorabies Virus Polyclonal Antibody

Pseudorabies Virus (PRV, Alphaherpesvirus Pseudorabies Virus, Aujeszky's Disease Virus, Suid Herpesvirus 1, Suid Herpesvirus Type 1)

Cat. Num. AAA616347

• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: Pseudorabies Virus; Polyclonal Antibody; Pseudorabies Virus (PRV; Alphaherpesvirus Pseudorabies Virus; Aujeszky's Disease Virus; Suid Herpesvirus 1; Suid Herpesvirus Type 1); Anti -Pseudorabies Virus (PRV; anti-Pseudorabies Virus antibody

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes PRV.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS containing 1 mg/ml BSA and 0.05% sodium azide.

• Applicable Applications for anti-Pseudorabies Virus antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot and Immunohistochemistry (paraffin).; Dilution: Western Blot: 0.2-1ug/ml. Detects proteins in the range 80-115kD representing various PRV proteins.; Immunohistochemistry (paraffin sections): 0.2-1ug/ml. Staining of PRV in rat hypothalamus from animals injected with PRV into the vitreous body of the eye results in intense staining of neurons in the superchiasmatic nucleus.
• Immunogen: Purified pseudorabies virus Bartha.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Immunohistochemical staining of PRV in rat hypothalamus from animals infected by injection of PRV into the vitreous body of the eye with MBS616347.)

Related Product Information for anti-Pseudorabies Virus antibody

Herpes simplex virus (HSV), varicella-zoster virus (VZV) and pseudorabies virus (PRV) comprise a family of neurotropic viruses known as alphaherpesviruses. PRV is primarily a disease of swine which serve as a reservoir for the virus and the principal source of natural infection for a diverse range of secondary hosts, including cattle, sheep, goats, dogs, cats, and many feral species. Humans and apes are refractory to PRV infection. PRV infects the epithelium of the host where it then spreads to axons of the peripheral nervous system (PNS). The virus opportunistically avails itself of the neuronal retrograde transport pathway which can facilitate transfer to the brain. This unique aspect of PRV allows it to be used as a powerful research tool to study neural connectivity and trace neuronal circuitry in the peripheral (PNS) and central nervous system (CNS).

Product Categories/Family for anti-Pseudorabies Virus antibody

Antibodies; Abs to Infectious Disease

NCBI and Uniprot Product Information

• NCBI GI #: 334093
• NCBI Official Full Name: Pseudorabies virus homologue of HSV-1 gene UL14; putative

Uniprot Description

Contributes to the nuclear transport of the viral transcriptional activator VP16 during the early phase of infection. Therefore, participates indirectly in the regulation of the immediate-early gene expression. Additionally, seems to be important for efficient nuclear targeting of capsids ().