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Western Blot (WB) (Western blot analysis of PSD4 using HT-29 whole cell lysates)

Rabbit anti-Human PSD4 Polyclonal Antibody | anti-PSD4 antibody

PSD4 Antibody

Gene Names
PSD4; TIC; EFA6B
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
PSD4; Polyclonal Antibody; PSD4 Antibody; EFA6B; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B; FLJ36237; FLJ37279; PH and SEC7 domain-containing protein 4; Pleckstrin homology and SEC7 domain-containing protein 4; Ppleckstrin and Sec7 domain containing 4; PSD4_HUMAN; SEC7 homolog antibody | telomeric of interleukin-1 cluster protein; Telomeric of interleukin-1 cluster protein; TIC; anti-PSD4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
PSD4 antibody detects endogenous levels of total PSD4
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1056
Applicable Applications for anti-PSD4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human PSD4
Subcellular Location
Cell Membrane. Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures.
Tissue Specificity
Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit, Dog
Similarity
Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of PSD4 using HT-29 whole cell lysates)

Western Blot (WB) (Western blot analysis of PSD4 using HT-29 whole cell lysates)
Related Product Information for anti-PSD4 antibody
Function: Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3, 4-bisphosphate, phosphatidylinositol 3, 5-bisphosphate and phosphatidylinositol 4, 5-bisphosphate.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 116 kDa
Predicted: 117 kDa
NCBI Official Full Name
PH and SEC7 domain-containing protein 4
NCBI Official Synonym Full Names
pleckstrin and Sec7 domain containing 4
NCBI Official Symbol
PSD4
NCBI Official Synonym Symbols
TIC; EFA6B
NCBI Protein Information
PH and SEC7 domain-containing protein 4
UniProt Protein Name
PH and SEC7 domain-containing protein 4
UniProt Gene Name
PSD4
UniProt Synonym Gene Names
; Exchange factor for ARF6 B

Uniprot Description

Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.

Research Articles on PSD4

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Product Notes

The PSD4 psd4 (Catalog #AAA9603019) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PSD4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PSD4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the PSD4 psd4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSD4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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