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Western Blot (WB) (Western BlotPositive WB detected in: HepG2 whole cell lysate, A2780 whole cell lysate, MCF-7 whole cell lysate, RAW264.7 whole cell lysateAll lanes: PRSS8 antibody at 2ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 37, 31 KDaObserved band size: 70 KDa)

Rabbit anti-Human PRSS8 Polyclonal Antibody | anti-PRSS8 antibody

PRSS8 Antibody

Gene Names
PRSS8; CAP1; PROSTASIN
Reactivity
Human
Applications
ELISA, Western Blot
Purity
>95%, Protein G purified
Synonyms
PRSS8; Polyclonal Antibody; PRSS8 Antibody; Prostasin; Channel-activating protease 1; CAP1; Serine protease 8; Prostasin light chain; Prostasin heavy chain; anti-PRSS8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
343
Applicable Applications for anti-PRSS8 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:500-1:5000
Immunogen
Recombinant Human Prostasin protein (185-319AA)
Conjugation
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: HepG2 whole cell lysate, A2780 whole cell lysate, MCF-7 whole cell lysate, RAW264.7 whole cell lysateAll lanes: PRSS8 antibody at 2ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 37, 31 KDaObserved band size: 70 KDa)

Western Blot (WB) (Western BlotPositive WB detected in: HepG2 whole cell lysate, A2780 whole cell lysate, MCF-7 whole cell lysate, RAW264.7 whole cell lysateAll lanes: PRSS8 antibody at 2ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 37, 31 KDaObserved band size: 70 KDa)
Related Product Information for anti-PRSS8 antibody
Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).
Product Categories/Family for anti-PRSS8 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,519 Da
NCBI Official Full Name
prostasin preproprotein
NCBI Official Synonym Full Names
serine protease 8
NCBI Official Symbol
PRSS8
NCBI Official Synonym Symbols
CAP1; PROSTASIN
NCBI Protein Information
prostasin
UniProt Protein Name
Prostasin
Protein Family
UniProt Gene Name
PRSS8
UniProt Synonym Gene Names
CAP1

NCBI Description

This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation. [provided by RefSeq, Feb 2016]

Uniprot Description

Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).

Research Articles on PRSS8

Similar Products

Product Notes

The PRSS8 prss8 (Catalog #AAA7106049) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRSS8 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PRSS8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500-1:5000. Researchers should empirically determine the suitability of the PRSS8 prss8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRSS8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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