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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using PRSS12 antibody.)

Rabbit anti-Mouse, Rat PRSS12 Polyclonal Antibody | anti-PRSS12 antibody

PRSS12 Polyclonal Antibody

Gene Names
PRSS12; MRT1; BSSP3; BSSP-3
Reactivity
Mouse, Rat
Applications
Western Blot
Purity
Affinity purification
Synonyms
PRSS12; Polyclonal Antibody; PRSS12 Polyclonal Antibody; BSSP-3; BSSP3; MRT1; neurotrypsin; anti-PRSS12 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 50% glycerol, pH7.4
Applicable Applications for anti-PRSS12 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human PRSS12 (NP_003610.2).
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using PRSS12 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using PRSS12 antibody.)
Related Product Information for anti-PRSS12 antibody
This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1).
Product Categories/Family for anti-PRSS12 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
97,067 Da
NCBI Official Full Name
neurotrypsin
NCBI Official Synonym Full Names
protease, serine, 12 (neurotrypsin, motopsin)
NCBI Official Symbol
PRSS12
NCBI Official Synonym Symbols
MRT1; BSSP3; BSSP-3
NCBI Protein Information
neurotrypsin; leydin; brain-specific serine protease 3
UniProt Protein Name
Neurotrypsin
Protein Family
UniProt Gene Name
PRSS12
UniProt Entry Name
NETR_HUMAN

Uniprot Description

PRSS12: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. Defects in PRSS12 are the cause of mental retardation autosomal recessive type 1 (MRT1). Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Belongs to the peptidase S1 family.

Protein type: Protease; Vesicle; EC 3.4.21.-; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 4q28.1

Cellular Component: axon; dendrite; extracellular region; plasma membrane; terminal button; cytoplasmic vesicle

Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity; scavenger receptor activity

Biological Process: receptor-mediated endocytosis; exocytosis; zymogen activation; proteolysis

Disease: Mental Retardation, Autosomal Recessive 1

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Product Notes

The PRSS12 prss12 (Catalog #AAA9432096) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRSS12 Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PRSS12 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PRSS12 prss12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRSS12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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