Rabbit anti-Human PRPS2 Polyclonal Antibody | anti-PRPS2 antibody
PRPS2 antibody
Immunohistochemistry: 1:100-1:500
Immunofluorescence: 1:100-1:200
Testing Data
(Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE PRPS2 antibody diluted at 1: 1000)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Hep3B xenograft, using PRPS2 antibody at 1: 100 dilution.)
Immunofluorescence (IF)
(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PRPS2 antibody at 1: 200 dilution.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Uniprot Description
PRPS2: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. Belongs to the ribose-phosphate pyrophosphokinase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Kinase, other; EC 2.7.6.1; Carbohydrate Metabolism - pentose phosphate pathway; Nucleotide Metabolism - purine
Chromosomal Location of Human Ortholog: Xp22.2
Molecular Function: ribose phosphate diphosphokinase activity; GDP binding; protein homodimerization activity; magnesium ion binding; kinase activity; carbohydrate binding; ADP binding; ATP binding; AMP binding
Biological Process: AMP biosynthetic process; organ regeneration; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; 5-phosphoribose 1-diphosphate biosynthetic process; phosphorylation
Research Articles on PRPS2
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Product Notes
The PRPS2 prps2 (Catalog #AAA9411174) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRPS2 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PRPS2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Western blotting: 1:500-1:3000 Immunohistochemistry: 1:100-1:500 Immunofluorescence: 1:100-1:200. Researchers should empirically determine the suitability of the PRPS2 prps2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRPS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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